Advanced Drug Carriers: A Review of Selected Protein, Polysaccharide, and Lipid Drug Delivery Platforms

Advanced Drug Carriers: A Review of Selected Protein, Polysaccharide, and Lipid Drug Delivery Platforms

8 January 2024 | Mateusz Jamroży, Sonia Kudlacik-Kramarczyk, Anna Drabczyk, Marcel Krzan
Advanced Drug Carriers: A Review of Selected Protein, Polysaccharide, and Lipid Drug Delivery Platforms This review discusses the development and application of advanced drug carriers based on lipids, polysaccharides, and proteins. These carriers are designed to improve drug delivery efficiency, enhance bioavailability, and minimize side effects. Lipid-based carriers include liposomes, lipid nanoemulsions, solid lipid nanoparticles (SLNs), and nanostructured lipid carriers (NLCs). Polysaccharide-based carriers include alginate and cellulose, while protein-based carriers include gelatin and albumin. These carriers are capable of efficiently loading therapeutic substances and controlling drug release. They also demonstrate desirable biocompatibility, making them promising candidates for drug therapy. The review highlights the potential of these carriers in improving therapeutic efficacy, particularly in cancer treatment. Lipid-based carriers, such as liposomes, have been used to deliver drugs with targeted delivery and controlled release. For example, magnetoliposomal nanocomposites have been developed to deliver anti-cancer drugs with targeted delivery. Lipid nanoemulsions have been used to enhance the solubility of lipophilic substances and improve drug delivery. Solid lipid nanoparticles and nanostructured lipid carriers have been developed to improve drug stability and release. Polysaccharide-based carriers, such as alginate, have been used to deliver drugs with controlled release and improved bioavailability. Protein-based carriers, such as gelatin and albumin, have been used to deliver drugs with targeted delivery and controlled release. The review concludes that these advanced drug carriers represent a promising approach to improving drug delivery and therapeutic efficacy. However, challenges such as stability, controlled release, and biocompatibility need to be addressed to fully realize their potential.Advanced Drug Carriers: A Review of Selected Protein, Polysaccharide, and Lipid Drug Delivery Platforms This review discusses the development and application of advanced drug carriers based on lipids, polysaccharides, and proteins. These carriers are designed to improve drug delivery efficiency, enhance bioavailability, and minimize side effects. Lipid-based carriers include liposomes, lipid nanoemulsions, solid lipid nanoparticles (SLNs), and nanostructured lipid carriers (NLCs). Polysaccharide-based carriers include alginate and cellulose, while protein-based carriers include gelatin and albumin. These carriers are capable of efficiently loading therapeutic substances and controlling drug release. They also demonstrate desirable biocompatibility, making them promising candidates for drug therapy. The review highlights the potential of these carriers in improving therapeutic efficacy, particularly in cancer treatment. Lipid-based carriers, such as liposomes, have been used to deliver drugs with targeted delivery and controlled release. For example, magnetoliposomal nanocomposites have been developed to deliver anti-cancer drugs with targeted delivery. Lipid nanoemulsions have been used to enhance the solubility of lipophilic substances and improve drug delivery. Solid lipid nanoparticles and nanostructured lipid carriers have been developed to improve drug stability and release. Polysaccharide-based carriers, such as alginate, have been used to deliver drugs with controlled release and improved bioavailability. Protein-based carriers, such as gelatin and albumin, have been used to deliver drugs with targeted delivery and controlled release. The review concludes that these advanced drug carriers represent a promising approach to improving drug delivery and therapeutic efficacy. However, challenges such as stability, controlled release, and biocompatibility need to be addressed to fully realize their potential.
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