Cardiac Troponin Serum Concentration Measurement Is Useful Not Only in the Diagnosis of Acute Cardiovascular Events

Cardiac Troponin Serum Concentration Measurement Is Useful Not Only in the Diagnosis of Acute Cardiovascular Events

21 February 2024 | Grzegorz K. Jakubiak
The article reviews the current state of knowledge regarding the role of cardiac troponin serum concentration in patients with chronic cardiovascular disease (CVD) and its relationship with subclinical cardiovascular dysfunction. Cardiac troponin is primarily used to diagnose acute coronary syndrome and is also important for risk stratification in pulmonary embolism. It serves as a general marker of myocardial damage, regardless of the underlying cause. Patients with CVDs, such as chronic coronary syndrome, chronic lower extremity ischemia, and cerebrovascular disease, have higher cardiac troponin levels compared to those without CVD. Additionally, cardiac troponin levels correlate with markers of subclinical cardiovascular dysfunction, including intima-media thickness, pulse wave velocity, ankle-brachial index, coronary artery calcium index, and flow-mediated dilation. However, further research is needed to validate these findings in different patient populations and clinical contexts. The article concludes by emphasizing the importance of cardiac troponin as a potential marker for cardiovascular screening and the need for more studies to explore its relationship with subclinical cardiovascular dysfunction.The article reviews the current state of knowledge regarding the role of cardiac troponin serum concentration in patients with chronic cardiovascular disease (CVD) and its relationship with subclinical cardiovascular dysfunction. Cardiac troponin is primarily used to diagnose acute coronary syndrome and is also important for risk stratification in pulmonary embolism. It serves as a general marker of myocardial damage, regardless of the underlying cause. Patients with CVDs, such as chronic coronary syndrome, chronic lower extremity ischemia, and cerebrovascular disease, have higher cardiac troponin levels compared to those without CVD. Additionally, cardiac troponin levels correlate with markers of subclinical cardiovascular dysfunction, including intima-media thickness, pulse wave velocity, ankle-brachial index, coronary artery calcium index, and flow-mediated dilation. However, further research is needed to validate these findings in different patient populations and clinical contexts. The article concludes by emphasizing the importance of cardiac troponin as a potential marker for cardiovascular screening and the need for more studies to explore its relationship with subclinical cardiovascular dysfunction.
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