This systematic review and meta-analysis examines the combined versus independent effects of exercise training (Ex) and intermittent fasting (IF) on body composition and cardiometabolic health in adults. The study included 11 randomized clinical trials with a total of 606 participants who were overweight or obese. The results show that combining Ex and IF significantly reduced body weight, BMI, body fat, visceral fat, and waist circumference compared to Ex alone, but did not significantly affect lean body mass (LBM). However, changes in cardiometabolic health markers such as fasting glucose, insulin, lipid profiles, blood pressure, and VO2max/peak were not significantly different between combined Ex and IF and standalone IF, except for VO2max/peak, which showed a significant increase with combined Ex and IF. The study concludes that combining Ex and IF is effective for weight and fat loss but has no additive or synergistic effects on other cardiometabolic health markers.This systematic review and meta-analysis examines the combined versus independent effects of exercise training (Ex) and intermittent fasting (IF) on body composition and cardiometabolic health in adults. The study included 11 randomized clinical trials with a total of 606 participants who were overweight or obese. The results show that combining Ex and IF significantly reduced body weight, BMI, body fat, visceral fat, and waist circumference compared to Ex alone, but did not significantly affect lean body mass (LBM). However, changes in cardiometabolic health markers such as fasting glucose, insulin, lipid profiles, blood pressure, and VO2max/peak were not significantly different between combined Ex and IF and standalone IF, except for VO2max/peak, which showed a significant increase with combined Ex and IF. The study concludes that combining Ex and IF is effective for weight and fat loss but has no additive or synergistic effects on other cardiometabolic health markers.