The study presents a novel approach to achieve blue circularly polarized organic afterglow (CPOA) materials by covalently self-confining isolated chiral chromophores within a polymer matrix. This method stabilizes the triplet excitons, suppresses non-radiative transitions, and enhances the luminescent dissymmetry factor, resulting in a blue emission band at 414 nm with a lifetime of 3.0 seconds and a luminescent dissymmetry factor of -10^-2. By doping colorful fluorescent molecules into the designed blue polymers, full-color CPOA systems are achieved, demonstrating versatile applications such as multiplex information encryption, functional fibers, and three-dimensional objects. The research paves the way for the development of blue CPOA materials with extended lifetimes and effective chirality, expanding their potential in various domains.The study presents a novel approach to achieve blue circularly polarized organic afterglow (CPOA) materials by covalently self-confining isolated chiral chromophores within a polymer matrix. This method stabilizes the triplet excitons, suppresses non-radiative transitions, and enhances the luminescent dissymmetry factor, resulting in a blue emission band at 414 nm with a lifetime of 3.0 seconds and a luminescent dissymmetry factor of -10^-2. By doping colorful fluorescent molecules into the designed blue polymers, full-color CPOA systems are achieved, demonstrating versatile applications such as multiplex information encryption, functional fibers, and three-dimensional objects. The research paves the way for the development of blue CPOA materials with extended lifetimes and effective chirality, expanding their potential in various domains.