Job strain as a risk factor for coronary heart disease: a collaborative meta-analysis of individual participant data

Job strain as a risk factor for coronary heart disease: a collaborative meta-analysis of individual participant data

2012 | Kivimäki M, Nyberg ST, Batty GD, et al, for the IPD-Work Consortium
This supplementary appendix provides details of the studies included in the collaborative meta-analysis on job strain as a risk factor for coronary heart disease (CHD). The IPD-Work Consortium analyzed data from multiple prospective cohort studies to assess the relationship between job strain and CHD. The studies included in the analysis are: Belstress, Copenhagen Psychosocial Questionnaire version I (COPSOQ-I), Danish Work Environment Cohort Study (DWECS), Finnish Public Sector study (FPS), Gazel, Health and Social Support (HeSSup), Intervention Project on Absence and Well-being (IPAW), Netherlands Working Conditions Survey (NWCS), Permanent Onderzoek Leefsituatie (POLS), Still Working, Whitehall II, and WOLF (Work, Lipids, and Fibrinogen) Stockholm and WOLF Norrland studies. Each study collected data on job strain and other relevant factors, and participants were eligible for the meta-analysis if they had available data on job strain. The analysis used different definitions of job strain, including job demand, job control, and combinations of both. The results showed that high job strain, defined as high demands and low control, was associated with an increased risk of CHD, rather than either component alone. The overall hazard ratio for the association between job strain and incident CHD was 1.23 (95% CI 1.08-1.39), consistent across all 13 cohorts. The studies were approved by relevant ethics committees and data protection agencies.This supplementary appendix provides details of the studies included in the collaborative meta-analysis on job strain as a risk factor for coronary heart disease (CHD). The IPD-Work Consortium analyzed data from multiple prospective cohort studies to assess the relationship between job strain and CHD. The studies included in the analysis are: Belstress, Copenhagen Psychosocial Questionnaire version I (COPSOQ-I), Danish Work Environment Cohort Study (DWECS), Finnish Public Sector study (FPS), Gazel, Health and Social Support (HeSSup), Intervention Project on Absence and Well-being (IPAW), Netherlands Working Conditions Survey (NWCS), Permanent Onderzoek Leefsituatie (POLS), Still Working, Whitehall II, and WOLF (Work, Lipids, and Fibrinogen) Stockholm and WOLF Norrland studies. Each study collected data on job strain and other relevant factors, and participants were eligible for the meta-analysis if they had available data on job strain. The analysis used different definitions of job strain, including job demand, job control, and combinations of both. The results showed that high job strain, defined as high demands and low control, was associated with an increased risk of CHD, rather than either component alone. The overall hazard ratio for the association between job strain and incident CHD was 1.23 (95% CI 1.08-1.39), consistent across all 13 cohorts. The studies were approved by relevant ethics committees and data protection agencies.
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[slides and audio] Job strain as a risk factor for coronary heart disease%3A a collaborative meta-analysis of individual participant data