The study investigates the presence of depressive disorders in hospitalized patients to prevent and reduce the risk of developing psychological pathology (anxious-depressive symptoms). Two tests were used: the General Health Questionnaire (GHQ-12) and the Personal Health Questionnaire (PHQ). The GHQ-12 assesses non-psychotic mental disorders and daily activity difficulties, while the PHQ detects ICD-10 depressive disorders. The tests were administered to 140 subjects from eight departments of a university hospital, medical faculty, and social services. Results showed that non-psychotic mental disorders were not detected in the groups, except for females, who showed some problems with insomnia and stress. The PHQ detected no major depressive symptoms in all groups. The experimental groups had more depressive symptoms than the control groups. The study concluded that depressive symptoms were present in a hospitalized population. Detecting these symptoms is important for protecting and caring for depressive disorders in both hospitalized and non-hospitalized populations. The GHQ-12 is a reliable tool with a Cronbach's alpha of 0.81, identifying two factors: general dysphoria and social dysfunction. The PHQ is a new tool for detecting ICD-10 depressive disorders, with high internal consistency and test-retest reliability. It is recommended as an accurate and cost-effective screening tool for identifying individuals at high risk of clinical depression in primary care settings. The study found that females in the control group had more insomnia and stress, while males in the experimental group had more depressive symptoms. Both tests revealed that hospitalized patients had more depressive symptoms than non-hospitalized individuals. The study highlights the importance of screening for depressive symptoms in hospitalized patients to prevent the chronicization of psychological distress. The results suggest that depression is more common in males, while anxiety-depressive symptoms are more common in females. The study emphasizes the need for psychological support and intervention programs for hospitalized patients.The study investigates the presence of depressive disorders in hospitalized patients to prevent and reduce the risk of developing psychological pathology (anxious-depressive symptoms). Two tests were used: the General Health Questionnaire (GHQ-12) and the Personal Health Questionnaire (PHQ). The GHQ-12 assesses non-psychotic mental disorders and daily activity difficulties, while the PHQ detects ICD-10 depressive disorders. The tests were administered to 140 subjects from eight departments of a university hospital, medical faculty, and social services. Results showed that non-psychotic mental disorders were not detected in the groups, except for females, who showed some problems with insomnia and stress. The PHQ detected no major depressive symptoms in all groups. The experimental groups had more depressive symptoms than the control groups. The study concluded that depressive symptoms were present in a hospitalized population. Detecting these symptoms is important for protecting and caring for depressive disorders in both hospitalized and non-hospitalized populations. The GHQ-12 is a reliable tool with a Cronbach's alpha of 0.81, identifying two factors: general dysphoria and social dysfunction. The PHQ is a new tool for detecting ICD-10 depressive disorders, with high internal consistency and test-retest reliability. It is recommended as an accurate and cost-effective screening tool for identifying individuals at high risk of clinical depression in primary care settings. The study found that females in the control group had more insomnia and stress, while males in the experimental group had more depressive symptoms. Both tests revealed that hospitalized patients had more depressive symptoms than non-hospitalized individuals. The study highlights the importance of screening for depressive symptoms in hospitalized patients to prevent the chronicization of psychological distress. The results suggest that depression is more common in males, while anxiety-depressive symptoms are more common in females. The study emphasizes the need for psychological support and intervention programs for hospitalized patients.