This case report presents a 41-year-old female patient diagnosed with Takayasu arteritis (TA), a vasculitis-panarteritis affecting the aortic arch and its major branches. The patient experienced chest pain, fatigue, and pain in both legs. The disease progressed over several months, leading to occlusion of the right subclavian artery and stenosis of the distal aorta. The diagnostic process involved detailed medical history, clinical examination, and angiography. Treatment included glucocorticoids in the early stages and bypass surgery for definitive stenosis and occlusion. The patient underwent an aorto-bifemoral bypass, which was successful, and subsequent carotid-superclavial bypass. The report emphasizes the importance of early diagnosis and timely surgical intervention to prevent complications. Key points include the clinical phases of TA, diagnostic criteria, and the role of surgery in managing the disease.This case report presents a 41-year-old female patient diagnosed with Takayasu arteritis (TA), a vasculitis-panarteritis affecting the aortic arch and its major branches. The patient experienced chest pain, fatigue, and pain in both legs. The disease progressed over several months, leading to occlusion of the right subclavian artery and stenosis of the distal aorta. The diagnostic process involved detailed medical history, clinical examination, and angiography. Treatment included glucocorticoids in the early stages and bypass surgery for definitive stenosis and occlusion. The patient underwent an aorto-bifemoral bypass, which was successful, and subsequent carotid-superclavial bypass. The report emphasizes the importance of early diagnosis and timely surgical intervention to prevent complications. Key points include the clinical phases of TA, diagnostic criteria, and the role of surgery in managing the disease.