The 2015 ESC/ERS Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension provide updated recommendations for the clinical management of pulmonary hypertension (PH). The guidelines are endorsed by several professional societies and cover various aspects of PH, including definitions, classifications, epidemiology, genetics, diagnosis, and treatment. Key changes from the 2009 guidelines include a simplified table of contents, updated clinical classifications, and new findings on gene mutations and associated conditions. The guidelines emphasize the importance of a multidisciplinary approach and highlight the need for comprehensive patient assessment, including clinical presentation, imaging, hemodynamic measurements, and genetic testing. Treatment options are discussed, with a focus on general measures, specific drug therapies, and supportive care. The guidelines aim to assist healthcare professionals in making informed decisions for individual patients, while acknowledging the final responsibility lies with the treating physician.The 2015 ESC/ERS Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension provide updated recommendations for the clinical management of pulmonary hypertension (PH). The guidelines are endorsed by several professional societies and cover various aspects of PH, including definitions, classifications, epidemiology, genetics, diagnosis, and treatment. Key changes from the 2009 guidelines include a simplified table of contents, updated clinical classifications, and new findings on gene mutations and associated conditions. The guidelines emphasize the importance of a multidisciplinary approach and highlight the need for comprehensive patient assessment, including clinical presentation, imaging, hemodynamic measurements, and genetic testing. Treatment options are discussed, with a focus on general measures, specific drug therapies, and supportive care. The guidelines aim to assist healthcare professionals in making informed decisions for individual patients, while acknowledging the final responsibility lies with the treating physician.