A prospective study of 25-hydroxyvitamin D (25(OH)D) and risk of myocardial infarction (MI) in men found that men with 25(OH)D levels below 15 ng/mL had a significantly higher risk of MI compared to those with levels of 30 ng/mL or higher. After adjusting for various factors, including family history, BMI, alcohol consumption, physical activity, and lipid levels, the association remained significant. Men with intermediate 25(OH)D levels (15.0–29.9 ng/mL) also had elevated risk compared to those with sufficient levels. The study suggests that optimal 25(OH)D levels should be at least 30 ng/mL to reduce MI risk. The study was conducted among 18,225 men from the Health Professionals Follow-Up Study, with 454 developing MI or fatal coronary heart disease over 10 years. Controls were selected based on age, blood draw date, and smoking status. The study found that lower 25(OH)D levels were associated with higher risk of MI, and this association was consistent across different subgroups. The study highlights the importance of maintaining adequate vitamin D levels to reduce cardiovascular risk. The results suggest that vitamin D deficiency may play a role in the development of atherosclerosis and coronary heart disease, and that maintaining optimal vitamin D levels could be a key factor in preventing MI. The study also notes that vitamin D levels are influenced by sun exposure, and that individuals in sun-rich environments tend to have higher 25(OH)D levels. The study is part of a larger body of research indicating that vitamin D may influence cardiovascular risk through various biological mechanisms, including vascular calcification, inflammation, and blood pressure regulation. The study concludes that maintaining 25(OH)D levels above 30 ng/mL is important for reducing MI risk.A prospective study of 25-hydroxyvitamin D (25(OH)D) and risk of myocardial infarction (MI) in men found that men with 25(OH)D levels below 15 ng/mL had a significantly higher risk of MI compared to those with levels of 30 ng/mL or higher. After adjusting for various factors, including family history, BMI, alcohol consumption, physical activity, and lipid levels, the association remained significant. Men with intermediate 25(OH)D levels (15.0–29.9 ng/mL) also had elevated risk compared to those with sufficient levels. The study suggests that optimal 25(OH)D levels should be at least 30 ng/mL to reduce MI risk. The study was conducted among 18,225 men from the Health Professionals Follow-Up Study, with 454 developing MI or fatal coronary heart disease over 10 years. Controls were selected based on age, blood draw date, and smoking status. The study found that lower 25(OH)D levels were associated with higher risk of MI, and this association was consistent across different subgroups. The study highlights the importance of maintaining adequate vitamin D levels to reduce cardiovascular risk. The results suggest that vitamin D deficiency may play a role in the development of atherosclerosis and coronary heart disease, and that maintaining optimal vitamin D levels could be a key factor in preventing MI. The study also notes that vitamin D levels are influenced by sun exposure, and that individuals in sun-rich environments tend to have higher 25(OH)D levels. The study is part of a larger body of research indicating that vitamin D may influence cardiovascular risk through various biological mechanisms, including vascular calcification, inflammation, and blood pressure regulation. The study concludes that maintaining 25(OH)D levels above 30 ng/mL is important for reducing MI risk.