The article reviews the advancements in organic field-effect transistors (OFETs) over the past 25 years, highlighting significant improvements in material performance, particularly in charge transport physics. Key discoveries have been published in Advanced Materials, with OFETs now outperforming amorphous silicon-based devices in many applications. The review focuses on the materials and device performance required for demanding future applications, such as active-matrix addressing for flexible OLED displays. It discusses the current understanding of charge transport physics in small-molecule and conjugated polymer materials, which have achieved field-effect mobilities exceeding 1 cm² V⁻¹ s⁻¹. The article also addresses the challenges in extracting robust mobility values from device characteristics and the potential for further improvements in performance. Finally, it explores the potential of OFETs for addressing demanding applications, including full-color, video, flexible OLED displays, and the role of material compatibility and mechanical properties in achieving these goals.The article reviews the advancements in organic field-effect transistors (OFETs) over the past 25 years, highlighting significant improvements in material performance, particularly in charge transport physics. Key discoveries have been published in Advanced Materials, with OFETs now outperforming amorphous silicon-based devices in many applications. The review focuses on the materials and device performance required for demanding future applications, such as active-matrix addressing for flexible OLED displays. It discusses the current understanding of charge transport physics in small-molecule and conjugated polymer materials, which have achieved field-effect mobilities exceeding 1 cm² V⁻¹ s⁻¹. The article also addresses the challenges in extracting robust mobility values from device characteristics and the potential for further improvements in performance. Finally, it explores the potential of OFETs for addressing demanding applications, including full-color, video, flexible OLED displays, and the role of material compatibility and mechanical properties in achieving these goals.