AGREE—Analytical GREENness Metric Approach and Software

AGREE—Analytical GREENness Metric Approach and Software

2020 | Francisco Pena-Pereira, Wojciech Wojnowski, Marek Tobiszewski
The article introduces the Analytical GREENness calculator (AGREE), a comprehensive and flexible tool for assessing the greenness of analytical procedures. AGREE is designed to address the multifaceted nature of green analytical chemistry (GAC), which involves evaluating criteria such as reagent toxicity, waste generation, energy consumption, and procedural steps. The assessment criteria are based on the 12 principles of GAC, transformed into a unified 0-1 scale, and weighted to reflect their importance. The final score is presented in a pictogram, providing an intuitive visual representation of the procedure's performance and strengths and weaknesses. The software is freely available and user-friendly, making it easy to perform assessments. The article also includes case studies demonstrating the applicability of AGREE to various analytical methodologies, highlighting its effectiveness in comparing different procedures based on their environmental impact.The article introduces the Analytical GREENness calculator (AGREE), a comprehensive and flexible tool for assessing the greenness of analytical procedures. AGREE is designed to address the multifaceted nature of green analytical chemistry (GAC), which involves evaluating criteria such as reagent toxicity, waste generation, energy consumption, and procedural steps. The assessment criteria are based on the 12 principles of GAC, transformed into a unified 0-1 scale, and weighted to reflect their importance. The final score is presented in a pictogram, providing an intuitive visual representation of the procedure's performance and strengths and weaknesses. The software is freely available and user-friendly, making it easy to perform assessments. The article also includes case studies demonstrating the applicability of AGREE to various analytical methodologies, highlighting its effectiveness in comparing different procedures based on their environmental impact.
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