This study investigates college instructors' perspectives on integrating AI literacy into the curriculum at Palestine Technical University Kadoorie (PTUK). Using a mixed-method approach, including a questionnaire and semi-structured interviews, the research aims to understand the current state of AI literacy in higher education and identify factors influencing instructors' perspectives. The findings reveal that college instructors perceive AI literacy as a weak element in the curriculum, with a particular emphasis on the need to achieve educational goals and address the lack of AI ethical guidelines and concepts. The study also highlights the influence of gender, technical skills, and academic rank on instructors' perspectives. Recommendations include the necessity to incorporate AI literacy into the curriculum across different disciplines and provide guidelines for its effective integration. The study contributes to the literature by bridging the gap in understanding AI literacy in higher education and offering insights for educators and policymakers.This study investigates college instructors' perspectives on integrating AI literacy into the curriculum at Palestine Technical University Kadoorie (PTUK). Using a mixed-method approach, including a questionnaire and semi-structured interviews, the research aims to understand the current state of AI literacy in higher education and identify factors influencing instructors' perspectives. The findings reveal that college instructors perceive AI literacy as a weak element in the curriculum, with a particular emphasis on the need to achieve educational goals and address the lack of AI ethical guidelines and concepts. The study also highlights the influence of gender, technical skills, and academic rank on instructors' perspectives. Recommendations include the necessity to incorporate AI literacy into the curriculum across different disciplines and provide guidelines for its effective integration. The study contributes to the literature by bridging the gap in understanding AI literacy in higher education and offering insights for educators and policymakers.