The authors use the Wide Field Camera 3 (WFC3) on the Hubble Space Telescope (HST) to reduce the uncertainty in the local value of the Hubble constant from 3.3% to 2.4%. This improvement is primarily due to new near-infrared observations of Cepheid variables in 11 host galaxies of recent Type Ia supernovae (SNe Ia), more than doubling the sample of reliable SNe Ia with Cepheid-calibrated distances to a total of 19. These observations leverage the magnitude-redshift relation based on approximately 300 SNe Ia at $z < 0.15$. The study also includes improvements such as a 33% reduction in the systematic uncertainty in the maser distance to NGC 4258, larger Cepheid samples in the Large Magellanic Cloud (LMC), a more robust distance to the LMC based on late-type detached eclipsing binaries (DEBs), HST observations of Cepheids in M31, and new HST-based trigonometric parallaxes for Milky Way (MW) Cepheids. The best estimate of the Hubble constant, combining the anchors NGC 4258, MW, and LMC, is 73.24 ± 1.74 km s$^{-1}$ Mpc$^{-1}$, yielding a 2.4% determination. This value is 3.4σ higher than the prediction by the ΛCDM model with 3 neutrino flavors and new Planck data, but the discrepancy reduces to 2.1σ relative to the prediction based on the more precise combination of WMAP+ACT+SPT+BAO observations, suggesting that systematic uncertainties in cosmic microwave background radiation measurements may play a role in the tension.The authors use the Wide Field Camera 3 (WFC3) on the Hubble Space Telescope (HST) to reduce the uncertainty in the local value of the Hubble constant from 3.3% to 2.4%. This improvement is primarily due to new near-infrared observations of Cepheid variables in 11 host galaxies of recent Type Ia supernovae (SNe Ia), more than doubling the sample of reliable SNe Ia with Cepheid-calibrated distances to a total of 19. These observations leverage the magnitude-redshift relation based on approximately 300 SNe Ia at $z < 0.15$. The study also includes improvements such as a 33% reduction in the systematic uncertainty in the maser distance to NGC 4258, larger Cepheid samples in the Large Magellanic Cloud (LMC), a more robust distance to the LMC based on late-type detached eclipsing binaries (DEBs), HST observations of Cepheids in M31, and new HST-based trigonometric parallaxes for Milky Way (MW) Cepheids. The best estimate of the Hubble constant, combining the anchors NGC 4258, MW, and LMC, is 73.24 ± 1.74 km s$^{-1}$ Mpc$^{-1}$, yielding a 2.4% determination. This value is 3.4σ higher than the prediction by the ΛCDM model with 3 neutrino flavors and new Planck data, but the discrepancy reduces to 2.1σ relative to the prediction based on the more precise combination of WMAP+ACT+SPT+BAO observations, suggesting that systematic uncertainties in cosmic microwave background radiation measurements may play a role in the tension.