This paper proposes a blockchain and trusted execution environment (TEE)-based privacy-preserving healthcare data sharing scheme that supports incremental updates. The scheme addresses the challenges of data ownership and privacy leakage in healthcare data sharing. It uses chameleon hash and TEE to achieve reliable incremental updates and verification without modifying on-chain data. Off-chain data are protected through symmetric encryption, while data verification, decryption, and computation are performed within TEE. The scheme ensures secure storage and sharing of personal healthcare data. Experimental results show the feasibility and effectiveness of the proposed scheme. The system model includes a shared blockchain (SB) and an updated blockchain (UB) to store shared transactions and incremental update records. The scheme supports off-chain incremental updates, ensuring data traceability and security. The system also includes smart contracts for access control and key authorization. The scheme reduces system overhead by avoiding the need to republish new records during incremental updates. The scheme is evaluated through simulations, demonstrating its reliability and efficiency. The scheme ensures data privacy and security while enabling secure and efficient healthcare data sharing.This paper proposes a blockchain and trusted execution environment (TEE)-based privacy-preserving healthcare data sharing scheme that supports incremental updates. The scheme addresses the challenges of data ownership and privacy leakage in healthcare data sharing. It uses chameleon hash and TEE to achieve reliable incremental updates and verification without modifying on-chain data. Off-chain data are protected through symmetric encryption, while data verification, decryption, and computation are performed within TEE. The scheme ensures secure storage and sharing of personal healthcare data. Experimental results show the feasibility and effectiveness of the proposed scheme. The system model includes a shared blockchain (SB) and an updated blockchain (UB) to store shared transactions and incremental update records. The scheme supports off-chain incremental updates, ensuring data traceability and security. The system also includes smart contracts for access control and key authorization. The scheme reduces system overhead by avoiding the need to republish new records during incremental updates. The scheme is evaluated through simulations, demonstrating its reliability and efficiency. The scheme ensures data privacy and security while enabling secure and efficient healthcare data sharing.