The article provides a comprehensive review of room-temperature sodium-sulfur (RT-Na/S) batteries, highlighting their potential as high-energy-density energy storage systems. However, practical applications are hindered by issues such as dendrite growth, unstable solid-electrolyte interphase (SEI), volume changes, and polysulfide shuttling. The review discusses recent advancements in Na metal anodes, S cathodes, electrolytes, and separators, emphasizing the importance of crucial parameters like depth of discharge (DOD), electrolyte-to-sulfur (E/S) ratio, and Na/S content. It proposes an empirical equation to estimate the actual energy density of RT-Na/S pouch cells under practical conditions and suggests rational values for these parameters to achieve high gravimetric energy density. The review also details various approaches to enhance the stability of Na metal anodes, including functional host material design, artificial SEI layers, current collector modifications, and liquid metal anodes. For S cathodes, it highlights the use of nanocomposite catalytic cathodes and single-atomic catalytic cathodes to improve reaction kinetics and reduce polysulfide dissolution. The article aims to bridge the gap between laboratory research and practical applications by providing practical insights and recommendations.The article provides a comprehensive review of room-temperature sodium-sulfur (RT-Na/S) batteries, highlighting their potential as high-energy-density energy storage systems. However, practical applications are hindered by issues such as dendrite growth, unstable solid-electrolyte interphase (SEI), volume changes, and polysulfide shuttling. The review discusses recent advancements in Na metal anodes, S cathodes, electrolytes, and separators, emphasizing the importance of crucial parameters like depth of discharge (DOD), electrolyte-to-sulfur (E/S) ratio, and Na/S content. It proposes an empirical equation to estimate the actual energy density of RT-Na/S pouch cells under practical conditions and suggests rational values for these parameters to achieve high gravimetric energy density. The review also details various approaches to enhance the stability of Na metal anodes, including functional host material design, artificial SEI layers, current collector modifications, and liquid metal anodes. For S cathodes, it highlights the use of nanocomposite catalytic cathodes and single-atomic catalytic cathodes to improve reaction kinetics and reduce polysulfide dissolution. The article aims to bridge the gap between laboratory research and practical applications by providing practical insights and recommendations.