A systematic review of healthcare applications for smartphones was conducted to classify and summarize smartphone-based healthcare technologies according to their functionalities. The study identified 83 applications across three categories: healthcare professionals (57 applications), medical or nursing students (11 applications), and patients (15 applications). The applications were grouped into seven categories for healthcare professionals, including disease diagnosis, drug reference, medical calculators, literature search, clinical communication, HIS clients, and medical training. For medical or nursing students, the applications focused on medical education. For patients, the applications focused on disease management with chronic illness, ENT-related conditions, fall-related conditions, and other conditions. The study found that disease diagnosis, drug reference, and medical calculator applications were reported as most useful by healthcare professionals and medical or nursing students. The use of smartphones in healthcare is increasing, and they are becoming important tools for evidence-based medicine at the point of care, mobile clinical communication, patient education, disease self-management, and remote monitoring. The study also highlighted the importance of smartphones in chronic disease management, clinical communication, and medical training. The applications were evaluated for their functionality, usability, and impact on healthcare practices. The study concluded that smartphones have significant potential in improving healthcare delivery and patient outcomes.A systematic review of healthcare applications for smartphones was conducted to classify and summarize smartphone-based healthcare technologies according to their functionalities. The study identified 83 applications across three categories: healthcare professionals (57 applications), medical or nursing students (11 applications), and patients (15 applications). The applications were grouped into seven categories for healthcare professionals, including disease diagnosis, drug reference, medical calculators, literature search, clinical communication, HIS clients, and medical training. For medical or nursing students, the applications focused on medical education. For patients, the applications focused on disease management with chronic illness, ENT-related conditions, fall-related conditions, and other conditions. The study found that disease diagnosis, drug reference, and medical calculator applications were reported as most useful by healthcare professionals and medical or nursing students. The use of smartphones in healthcare is increasing, and they are becoming important tools for evidence-based medicine at the point of care, mobile clinical communication, patient education, disease self-management, and remote monitoring. The study also highlighted the importance of smartphones in chronic disease management, clinical communication, and medical training. The applications were evaluated for their functionality, usability, and impact on healthcare practices. The study concluded that smartphones have significant potential in improving healthcare delivery and patient outcomes.