A systematic review of AI applications in sustainable building lifecycles explores how AI enhances sustainability through design, construction, and operations. AI technologies, such as machine learning, digital twins, and IoT, improve energy efficiency, predictive maintenance, and design optimization. However, challenges like cost, data security, and implementation barriers hinder widespread adoption. The review highlights AI's role in reducing waste, optimizing resource use, and enhancing building performance. It also identifies the need for further research to address technical and practical challenges in AI integration. The study emphasizes the importance of AI in sustainable building practices, offering solutions for efficient construction, operational efficiency, and long-term sustainability. The review outlines a technological roadmap for AI integration, focusing on data infrastructure, AI applications, and workforce development. It concludes that AI has the potential to significantly transform the building industry, promoting sustainability and efficiency across all stages of a building's lifecycle.A systematic review of AI applications in sustainable building lifecycles explores how AI enhances sustainability through design, construction, and operations. AI technologies, such as machine learning, digital twins, and IoT, improve energy efficiency, predictive maintenance, and design optimization. However, challenges like cost, data security, and implementation barriers hinder widespread adoption. The review highlights AI's role in reducing waste, optimizing resource use, and enhancing building performance. It also identifies the need for further research to address technical and practical challenges in AI integration. The study emphasizes the importance of AI in sustainable building practices, offering solutions for efficient construction, operational efficiency, and long-term sustainability. The review outlines a technological roadmap for AI integration, focusing on data infrastructure, AI applications, and workforce development. It concludes that AI has the potential to significantly transform the building industry, promoting sustainability and efficiency across all stages of a building's lifecycle.