This study presents a bibliometric analysis of South Africa's Water-Energy-Food (WEF) nexus research landscape between 2011 and 2024 using the Scopus database. The analysis highlights the interconnectedness of sustainable development, resource management, sustainability challenges, and resilience strategies in the WEF Nexus in South Africa. It identifies critical research gaps in addressing socio-economic dimensions, policy and governance aspects, technological innovation, and human resource development within the WEF Nexus framework. The study reveals the transformative potential of blockchain technology in revolutionizing resource management in South Africa by leveraging its decentralized and transparent nature to enhance efficiency, transparency, and sustainability in resource allocation and distribution. The research identifies four thematic clusters: Sustainable Development, Resource Management, Sustainability Challenges, and Integrated Resilience Strategy. These clusters reflect the key areas of focus in WEF Nexus research, including sustainable practices, resource management, environmental and social challenges, and integrated approaches to address these issues. The study also highlights the importance of human capital development and technological adoption, particularly blockchain technology, in operationalizing the WEF Nexus. The study proposes a Human Capital Development and Technological Adoption Approach to enhance the operationalization of the WEF Nexus in South Africa. This approach emphasizes the integration of human expertise and technological advancements to address the interrelations and interactions within the nexus. The use of blockchain technology is highlighted as a promising solution for improving transparency, efficiency, and sustainability in resource management. The study concludes by recommending that the government, policymakers, and researchers invest in capacity-building initiatives to bolster human resources' education, skills, and overall capabilities in the WEF Nexus. It also suggests embracing 4IR technology, such as blockchain, as a transparent and effective resource management instrument.This study presents a bibliometric analysis of South Africa's Water-Energy-Food (WEF) nexus research landscape between 2011 and 2024 using the Scopus database. The analysis highlights the interconnectedness of sustainable development, resource management, sustainability challenges, and resilience strategies in the WEF Nexus in South Africa. It identifies critical research gaps in addressing socio-economic dimensions, policy and governance aspects, technological innovation, and human resource development within the WEF Nexus framework. The study reveals the transformative potential of blockchain technology in revolutionizing resource management in South Africa by leveraging its decentralized and transparent nature to enhance efficiency, transparency, and sustainability in resource allocation and distribution. The research identifies four thematic clusters: Sustainable Development, Resource Management, Sustainability Challenges, and Integrated Resilience Strategy. These clusters reflect the key areas of focus in WEF Nexus research, including sustainable practices, resource management, environmental and social challenges, and integrated approaches to address these issues. The study also highlights the importance of human capital development and technological adoption, particularly blockchain technology, in operationalizing the WEF Nexus. The study proposes a Human Capital Development and Technological Adoption Approach to enhance the operationalization of the WEF Nexus in South Africa. This approach emphasizes the integration of human expertise and technological advancements to address the interrelations and interactions within the nexus. The use of blockchain technology is highlighted as a promising solution for improving transparency, efficiency, and sustainability in resource management. The study concludes by recommending that the government, policymakers, and researchers invest in capacity-building initiatives to bolster human resources' education, skills, and overall capabilities in the WEF Nexus. It also suggests embracing 4IR technology, such as blockchain, as a transparent and effective resource management instrument.