This chapter of the dissertation by François Dekker et al. investigates patients' preferences for prophylactic medication in managing migraine. The study, conducted in three general practices, surveyed 283 patients diagnosed with migraine or prescribed migraine medication, with 166 completing the questionnaire. The results show that 55% of patients with two or more monthly attacks wanted to use prophylaxis, but only 8% actually did so. The study found that frequency, duration, severity, and impact of migraine attacks, as well as the patient's confidence in discussing prophylaxis with their GP, were significant factors in their willingness to consider prophylaxis. Most patients felt confident to approach their GP about prophylaxis, but a significant subgroup preferred an active approach by their physician. The study suggests that GPs can play a more active role in optimizing migraine therapy, potentially reducing patient disability and improving quality of life.This chapter of the dissertation by François Dekker et al. investigates patients' preferences for prophylactic medication in managing migraine. The study, conducted in three general practices, surveyed 283 patients diagnosed with migraine or prescribed migraine medication, with 166 completing the questionnaire. The results show that 55% of patients with two or more monthly attacks wanted to use prophylaxis, but only 8% actually did so. The study found that frequency, duration, severity, and impact of migraine attacks, as well as the patient's confidence in discussing prophylaxis with their GP, were significant factors in their willingness to consider prophylaxis. Most patients felt confident to approach their GP about prophylaxis, but a significant subgroup preferred an active approach by their physician. The study suggests that GPs can play a more active role in optimizing migraine therapy, potentially reducing patient disability and improving quality of life.