A life-course approach to women's health is being introduced to address the need for improved health outcomes for women and girls as part of achieving global health equity. Women, making up half of humanity, are often overlooked in medical research, which tends to focus mainly on reproductive health rather than the leading causes of death, such as cardiovascular disease and cancer. Sociocultural factors, including discrimination and power imbalances, significantly impact women's health but are rarely studied. The medical community must prioritize women's health, including transgender and non-binary individuals, to achieve equity. Women are a major part of the global health workforce, so their health affects entire communities. The new series highlights the unique ways women experience diseases, often due to biological and sociocultural factors. Many women's health conditions, such as endometriosis and menopause, are underfunded despite their significant impact. Recent research offers hope, but more funding and attention are needed. Diagnostic delays are common, often due to sociocultural barriers. Intimate partner violence, especially among transgender and women of color, has long-term health impacts. Research should reflect the needs of the population, with more women in leadership roles. Data collection on sex and gender is essential, and journals should adopt guidelines to ensure this. The series aims to spark discussions on improving women's health as part of global health equity.A life-course approach to women's health is being introduced to address the need for improved health outcomes for women and girls as part of achieving global health equity. Women, making up half of humanity, are often overlooked in medical research, which tends to focus mainly on reproductive health rather than the leading causes of death, such as cardiovascular disease and cancer. Sociocultural factors, including discrimination and power imbalances, significantly impact women's health but are rarely studied. The medical community must prioritize women's health, including transgender and non-binary individuals, to achieve equity. Women are a major part of the global health workforce, so their health affects entire communities. The new series highlights the unique ways women experience diseases, often due to biological and sociocultural factors. Many women's health conditions, such as endometriosis and menopause, are underfunded despite their significant impact. Recent research offers hope, but more funding and attention are needed. Diagnostic delays are common, often due to sociocultural barriers. Intimate partner violence, especially among transgender and women of color, has long-term health impacts. Research should reflect the needs of the population, with more women in leadership roles. Data collection on sex and gender is essential, and journals should adopt guidelines to ensure this. The series aims to spark discussions on improving women's health as part of global health equity.