This study conducted a two-site, randomized controlled trial to compare the efficacy of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) and Child-Centered Therapy (CCT) in treating posttraumatic stress disorder (PTSD) and related emotional and behavioral problems in children who have suffered sexual abuse. Two hundred and twenty-nine children aged 8-14 years, along with their primary caretakers, were randomly assigned to either TF-CBT or CCT. The results showed that children assigned to TF-CBT demonstrated significantly greater improvement in PTSD, depression, behavior problems, shame, and abuse-related attributions compared to those assigned to CCT. Similarly, parents assigned to TF-CBT reported greater improvements in their own self-reported levels of depression, abuse-specific distress, support of the child, and effective parenting practices. The study adds to the growing evidence supporting the efficacy of TF-CBT for children suffering from PTSD symptoms resulting from sexual abuse.This study conducted a two-site, randomized controlled trial to compare the efficacy of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) and Child-Centered Therapy (CCT) in treating posttraumatic stress disorder (PTSD) and related emotional and behavioral problems in children who have suffered sexual abuse. Two hundred and twenty-nine children aged 8-14 years, along with their primary caretakers, were randomly assigned to either TF-CBT or CCT. The results showed that children assigned to TF-CBT demonstrated significantly greater improvement in PTSD, depression, behavior problems, shame, and abuse-related attributions compared to those assigned to CCT. Similarly, parents assigned to TF-CBT reported greater improvements in their own self-reported levels of depression, abuse-specific distress, support of the child, and effective parenting practices. The study adds to the growing evidence supporting the efficacy of TF-CBT for children suffering from PTSD symptoms resulting from sexual abuse.