A self-regulatory cell-wall-sensing module at cell edges controls plant growth Plant cells coordinate growth through turgor pressure and cell wall mechanics. This study identifies two receptor-like proteins, RLP4 and RLP4-L1, localized at cell edges, which respond to changes in cell wall mechanics and contribute to directional growth control in Arabidopsis. RLP4s are transported to cell edges via RAB-A5c-mediated trafficking and stabilize at the cell surface through interaction with cell wall ligands. They are endocytosed when not associated with the cell wall, enabling rapid response to changes in cell wall status. RLP4s are involved in RAB-A5c patterning and growth control, and their function is essential for directional growth during interphase. The study proposes a model where RLP4s act as a scaffold for a signaling module that controls RAB-A5c-mediated transport, integrating cell wall mechanical feedback into directional growth. This mechanism allows plants to adapt growth in response to mechanical stresses, ensuring tissue integrity. The findings highlight the role of cell edges in sensing and responding to cell wall status, providing a framework for understanding plant growth regulation.A self-regulatory cell-wall-sensing module at cell edges controls plant growth Plant cells coordinate growth through turgor pressure and cell wall mechanics. This study identifies two receptor-like proteins, RLP4 and RLP4-L1, localized at cell edges, which respond to changes in cell wall mechanics and contribute to directional growth control in Arabidopsis. RLP4s are transported to cell edges via RAB-A5c-mediated trafficking and stabilize at the cell surface through interaction with cell wall ligands. They are endocytosed when not associated with the cell wall, enabling rapid response to changes in cell wall status. RLP4s are involved in RAB-A5c patterning and growth control, and their function is essential for directional growth during interphase. The study proposes a model where RLP4s act as a scaffold for a signaling module that controls RAB-A5c-mediated transport, integrating cell wall mechanical feedback into directional growth. This mechanism allows plants to adapt growth in response to mechanical stresses, ensuring tissue integrity. The findings highlight the role of cell edges in sensing and responding to cell wall status, providing a framework for understanding plant growth regulation.