The study by Leschka et al. (2005) investigates the accuracy of 64-slice computed tomography (CT) angiography in assessing hemodynamically significant stenoses of coronary arteries. The research involved 67 patients (50 male, 17 female; mean age 60.1 ± 10.5 years) with suspected coronary artery disease (CAD). CT angiography was performed and compared with invasive coronary angiography (ICA). All vessels ≥1.5 mm were evaluated for significant stenosis (diameter reduction >50%). ICA identified 18% (176/1005) of affected segments, while CT correctly identified all 20 patients with no significant stenosis on ICA. The overall sensitivity for classifying stenoses was 94%, specificity was 97%, positive predictive value was 87%, and negative predictive value was 99%. The study concludes that 64-slice CT provides high diagnostic accuracy in assessing coronary artery stenoses, with no segments needing exclusion from analysis. However, extensive arterial wall calcifications still impair vessel assessment. Further studies are needed to determine the threshold for reliable assessment and to examine patient populations with a lower pre-test probability of CAD.The study by Leschka et al. (2005) investigates the accuracy of 64-slice computed tomography (CT) angiography in assessing hemodynamically significant stenoses of coronary arteries. The research involved 67 patients (50 male, 17 female; mean age 60.1 ± 10.5 years) with suspected coronary artery disease (CAD). CT angiography was performed and compared with invasive coronary angiography (ICA). All vessels ≥1.5 mm were evaluated for significant stenosis (diameter reduction >50%). ICA identified 18% (176/1005) of affected segments, while CT correctly identified all 20 patients with no significant stenosis on ICA. The overall sensitivity for classifying stenoses was 94%, specificity was 97%, positive predictive value was 87%, and negative predictive value was 99%. The study concludes that 64-slice CT provides high diagnostic accuracy in assessing coronary artery stenoses, with no segments needing exclusion from analysis. However, extensive arterial wall calcifications still impair vessel assessment. Further studies are needed to determine the threshold for reliable assessment and to examine patient populations with a lower pre-test probability of CAD.