The paper introduces the Open-World Mobile Manipulation System, a full-stack approach to operate articulated objects such as doors, cabinets, drawers, and refrigerators in unstructured environments. The system uses an adaptive learning framework that initially learns from a small set of data through behavior cloning and then adapts to novel objects through online practice. A low-cost, versatile, and agile mobile manipulation hardware platform is developed, capable of safe and autonomous online adaptation with a cost of around 25,000 USD. Experiments conducted on 20 articulated objects across 4 buildings at CMU show that the system's success rate increases from 50% to 95% after online adaptation. The paper also discusses related work in adaptive real-world robot learning, learning-based mobile manipulation systems, and door manipulation, and provides details on the adaptive learning framework, hardware design, and experimental results.The paper introduces the Open-World Mobile Manipulation System, a full-stack approach to operate articulated objects such as doors, cabinets, drawers, and refrigerators in unstructured environments. The system uses an adaptive learning framework that initially learns from a small set of data through behavior cloning and then adapts to novel objects through online practice. A low-cost, versatile, and agile mobile manipulation hardware platform is developed, capable of safe and autonomous online adaptation with a cost of around 25,000 USD. Experiments conducted on 20 articulated objects across 4 buildings at CMU show that the system's success rate increases from 50% to 95% after online adaptation. The paper also discusses related work in adaptive real-world robot learning, learning-based mobile manipulation systems, and door manipulation, and provides details on the adaptive learning framework, hardware design, and experimental results.