Advanced oxidation processes (AOPs) are effective in removing pharmaceuticals from water. Pharmaceuticals are commonly found in natural and wastewater bodies, as well as drinking water, and they do not readily biodegrade, posing ongoing health and environmental risks. AOPs such as photo-Fenton, sonolysis, electrochemical oxidation, radiation, and ozonation are used to degrade pharmaceuticals by utilizing the high reactivity of hydroxyl radicals to oxidize organic compounds into harmless products. This review summarizes recent studies on the application of AOPs for pharmaceutical degradation. It discusses factors affecting the effectiveness of TiO₂-mediated photocatalytic treatment in degrading pharmaceutical residues. The review highlights the success of AOPs in removing pharmaceuticals from various water matrices and outlines recommendations for future research. The article is structured into sections including an introduction, status of pharmaceutical pollution, AOPs as a tool for degradation, TiO₂ photocatalytic degradation, and conclusions and future outlook. The study emphasizes the importance of AOPs in addressing pharmaceutical pollution and suggests further research to improve their efficiency and applicability. Keywords: removal, pharmaceuticals, wastewater, photocatalysis, advanced oxidation processes.Advanced oxidation processes (AOPs) are effective in removing pharmaceuticals from water. Pharmaceuticals are commonly found in natural and wastewater bodies, as well as drinking water, and they do not readily biodegrade, posing ongoing health and environmental risks. AOPs such as photo-Fenton, sonolysis, electrochemical oxidation, radiation, and ozonation are used to degrade pharmaceuticals by utilizing the high reactivity of hydroxyl radicals to oxidize organic compounds into harmless products. This review summarizes recent studies on the application of AOPs for pharmaceutical degradation. It discusses factors affecting the effectiveness of TiO₂-mediated photocatalytic treatment in degrading pharmaceutical residues. The review highlights the success of AOPs in removing pharmaceuticals from various water matrices and outlines recommendations for future research. The article is structured into sections including an introduction, status of pharmaceutical pollution, AOPs as a tool for degradation, TiO₂ photocatalytic degradation, and conclusions and future outlook. The study emphasizes the importance of AOPs in addressing pharmaceutical pollution and suggests further research to improve their efficiency and applicability. Keywords: removal, pharmaceuticals, wastewater, photocatalysis, advanced oxidation processes.