This review discusses recent advances in 3D bioprinting for regenerative medicine applications, focusing on the development of bioinks and bioprinting techniques to regenerate various tissues and organs, including bone, cartilage, cardiovascular, neural, skin, and organs such as liver, kidney, pancreas, and lungs. The review highlights the importance of bioink properties, such as gelation, rheological, mechanical, and biological characteristics, which are crucial for successful bioprinting. It also discusses the different 3D bioprinting techniques, including extrusion-based, jetting-based, and vat polymerization-based bioprinting, and their respective advantages and challenges. The review emphasizes the need for bioinks that can mimic the mechanical and biological properties of native tissues, as well as the importance of cell viability and functionality in bioprinted constructs. It also discusses the use of various biomaterials, such as natural and synthetic biopolymers, inks, and nanoparticles, to enhance the properties of bioinks. The review highlights the potential of 3D bioprinting in creating patient-specific implants and scaffolds that can support tissue regeneration and organ transplantation. It also discusses the challenges and limitations of current bioprinting technologies, such as limited printing accuracy, cell viability, and the need for further research to improve the scalability and functionality of bioprinted constructs. The review concludes that 3D bioprinting has the potential to revolutionize regenerative medicine by enabling the creation of functional artificial organs and tissues.This review discusses recent advances in 3D bioprinting for regenerative medicine applications, focusing on the development of bioinks and bioprinting techniques to regenerate various tissues and organs, including bone, cartilage, cardiovascular, neural, skin, and organs such as liver, kidney, pancreas, and lungs. The review highlights the importance of bioink properties, such as gelation, rheological, mechanical, and biological characteristics, which are crucial for successful bioprinting. It also discusses the different 3D bioprinting techniques, including extrusion-based, jetting-based, and vat polymerization-based bioprinting, and their respective advantages and challenges. The review emphasizes the need for bioinks that can mimic the mechanical and biological properties of native tissues, as well as the importance of cell viability and functionality in bioprinted constructs. It also discusses the use of various biomaterials, such as natural and synthetic biopolymers, inks, and nanoparticles, to enhance the properties of bioinks. The review highlights the potential of 3D bioprinting in creating patient-specific implants and scaffolds that can support tissue regeneration and organ transplantation. It also discusses the challenges and limitations of current bioprinting technologies, such as limited printing accuracy, cell viability, and the need for further research to improve the scalability and functionality of bioprinted constructs. The review concludes that 3D bioprinting has the potential to revolutionize regenerative medicine by enabling the creation of functional artificial organs and tissues.