This review article explores the advancements in nanoarchitectonics, focusing on the assembly of particles into functional materials and devices. It discusses both static and dynamic methods of particle assembly, emphasizing their applications in biomaterial sciences. Static methods rely on equilibrium interactions such as electrostatic, magnetic, or capillary forces, while dynamic methods involve external stimuli like electric fields, magnetic fields, light, or sound to manipulate particles in a non-equilibrium state. The article highlights the advantages and limitations of these methods, along with the nanoarchitectonic principles guiding the formation of desired structures and functions. Examples of biomaterials and devices fabricated using particle assembly, such as biosensors, drug delivery systems, tissue engineering scaffolds, and artificial organs, are provided. The review concludes by outlining future challenges and opportunities in particle assembly for biomaterial sciences, emphasizing the need for continuous research to refine methodologies and improve efficiency in nanomaterial synthesis. The potential implications of these advancements in healthcare, technology, energy storage, environmental science, and electronics are significant.This review article explores the advancements in nanoarchitectonics, focusing on the assembly of particles into functional materials and devices. It discusses both static and dynamic methods of particle assembly, emphasizing their applications in biomaterial sciences. Static methods rely on equilibrium interactions such as electrostatic, magnetic, or capillary forces, while dynamic methods involve external stimuli like electric fields, magnetic fields, light, or sound to manipulate particles in a non-equilibrium state. The article highlights the advantages and limitations of these methods, along with the nanoarchitectonic principles guiding the formation of desired structures and functions. Examples of biomaterials and devices fabricated using particle assembly, such as biosensors, drug delivery systems, tissue engineering scaffolds, and artificial organs, are provided. The review concludes by outlining future challenges and opportunities in particle assembly for biomaterial sciences, emphasizing the need for continuous research to refine methodologies and improve efficiency in nanomaterial synthesis. The potential implications of these advancements in healthcare, technology, energy storage, environmental science, and electronics are significant.