The study compares the aerosol and surface stability of SARS-CoV-2 with SARS-CoV-1, the most closely related human coronavirus. Using a Bayesian regression model, the researchers evaluated the stability of both viruses in aerosols and on various surfaces, including plastic, stainless steel, copper, and cardboard. SARS-CoV-2 remained viable in aerosols for up to 3 hours, with a reduction in infectious titer from 10^3.5 to 10^3.7 TCID50 per liter of air. On surfaces, SARS-CoV-2 was more stable on plastic and stainless steel, detectable up to 72 hours, while on copper and cardboard, it was undetectable after 4 and 24 hours, respectively. The half-lives of both viruses were similar in aerosols and on copper, but SARS-CoV-2 had a longer half-life on stainless steel and plastic. The findings suggest that SARS-CoV-2 can remain infectious in aerosols and on surfaces for extended periods, indicating plausible aerosol and fomite transmission. These results align with previous studies on SARS-CoV-1, highlighting the potential for nosocomial spread and super-spreading events.The study compares the aerosol and surface stability of SARS-CoV-2 with SARS-CoV-1, the most closely related human coronavirus. Using a Bayesian regression model, the researchers evaluated the stability of both viruses in aerosols and on various surfaces, including plastic, stainless steel, copper, and cardboard. SARS-CoV-2 remained viable in aerosols for up to 3 hours, with a reduction in infectious titer from 10^3.5 to 10^3.7 TCID50 per liter of air. On surfaces, SARS-CoV-2 was more stable on plastic and stainless steel, detectable up to 72 hours, while on copper and cardboard, it was undetectable after 4 and 24 hours, respectively. The half-lives of both viruses were similar in aerosols and on copper, but SARS-CoV-2 had a longer half-life on stainless steel and plastic. The findings suggest that SARS-CoV-2 can remain infectious in aerosols and on surfaces for extended periods, indicating plausible aerosol and fomite transmission. These results align with previous studies on SARS-CoV-1, highlighting the potential for nosocomial spread and super-spreading events.