Ag-doped CNT/HAP nanohybrids in a PLLA bone scaffold show significant antibacterial activity. In this study, silver (Ag)-doped CNT/HAP (CNT/Ag-HAP) nanohybrids were synthesized by replacing calcium ions (Ca²⁺) in the HAP lattice with silver ions (Ag⁺) using an ion doping technique under hydrothermal conditions. The doping process involved the partial replacement of Ca²⁺ in the HAP lattice by Ag⁺ and the in situ synthesis of Ag-HAP nanoparticles on CNT. The resulting CNT/Ag-HAP nanohybrids were introduced into a PLLA matrix via laser-based powder bed fusion (PBF-LB) to fabricate PLLA/CNT/Ag-HAP scaffolds that showed sustained antibacterial activity. The antibacterial effectiveness of the scaffolds was 92.65%, attributed to the broad-spectrum antibacterial activity of Ag⁺ and the physical destruction of bacterial structures due to the sharp edge structure of CNT. The scaffolds also exhibited enhanced mechanical properties, with tensile and compressive strengths of 8.49 MPa and 19.72 MPa, respectively. Additionally, the scaffolds showed good bioactivity and cytocompatibility, including the ability to form apatite layers and to promote the adhesion and proliferation of human osteoblast-like cells (MG63 cells). Artificial bone scaffolds are important for bone repair and regeneration. However, they may cause serious bacterial infections when transplanted into the human body, which can undermine their intended function. To address this, antibacterial strategies are needed to endow bone scaffolds with antibacterial properties. Antibiotics-loaded scaffolds have been developed, but their overuse has led to the increasing incidence of multidrug-resistant bacteria. Inorganic antimicrobial agents, including silver (Ag), copper (Cu), and zinc (Zn), have become important for antibiotic research due to their lower likelihood of inducing drug resistance. However, composite scaffolds directly loaded with Ag nanoparticles and/or other antibacterial nanometals may weaken antibacterial activity and cause burst releases of nanoparticles. Doping procedures using antibacterial metal ions can compensate for this effect by altering the crystal structures of substances, thereby obtaining sustained antibacterial activity. Thus, it would be desirable to achieve the continuous release of antibacterial substances from scaffolds by doping antibacterial metal ions into the CNT/HAP crystal structure. HAP (Ca₁₀(PO₄)₆(OH)₂) is a hexagonal crystal system that includes two types of Ca²⁺ in different positions within its unit cell. This special structural composition provides HAP with a strong ion exchange ability.Ag-doped CNT/HAP nanohybrids in a PLLA bone scaffold show significant antibacterial activity. In this study, silver (Ag)-doped CNT/HAP (CNT/Ag-HAP) nanohybrids were synthesized by replacing calcium ions (Ca²⁺) in the HAP lattice with silver ions (Ag⁺) using an ion doping technique under hydrothermal conditions. The doping process involved the partial replacement of Ca²⁺ in the HAP lattice by Ag⁺ and the in situ synthesis of Ag-HAP nanoparticles on CNT. The resulting CNT/Ag-HAP nanohybrids were introduced into a PLLA matrix via laser-based powder bed fusion (PBF-LB) to fabricate PLLA/CNT/Ag-HAP scaffolds that showed sustained antibacterial activity. The antibacterial effectiveness of the scaffolds was 92.65%, attributed to the broad-spectrum antibacterial activity of Ag⁺ and the physical destruction of bacterial structures due to the sharp edge structure of CNT. The scaffolds also exhibited enhanced mechanical properties, with tensile and compressive strengths of 8.49 MPa and 19.72 MPa, respectively. Additionally, the scaffolds showed good bioactivity and cytocompatibility, including the ability to form apatite layers and to promote the adhesion and proliferation of human osteoblast-like cells (MG63 cells). Artificial bone scaffolds are important for bone repair and regeneration. However, they may cause serious bacterial infections when transplanted into the human body, which can undermine their intended function. To address this, antibacterial strategies are needed to endow bone scaffolds with antibacterial properties. Antibiotics-loaded scaffolds have been developed, but their overuse has led to the increasing incidence of multidrug-resistant bacteria. Inorganic antimicrobial agents, including silver (Ag), copper (Cu), and zinc (Zn), have become important for antibiotic research due to their lower likelihood of inducing drug resistance. However, composite scaffolds directly loaded with Ag nanoparticles and/or other antibacterial nanometals may weaken antibacterial activity and cause burst releases of nanoparticles. Doping procedures using antibacterial metal ions can compensate for this effect by altering the crystal structures of substances, thereby obtaining sustained antibacterial activity. Thus, it would be desirable to achieve the continuous release of antibacterial substances from scaffolds by doping antibacterial metal ions into the CNT/HAP crystal structure. HAP (Ca₁₀(PO₄)₆(OH)₂) is a hexagonal crystal system that includes two types of Ca²⁺ in different positions within its unit cell. This special structural composition provides HAP with a strong ion exchange ability.