Received for publication 14 October 1987 and in revised form 28 December 1987. | Siu L. Hui, Charles W. Slemenda, and C. Conrad Johnston, Jr.
This study investigates the relationship between bone mass and the risk of fracture in 521 Caucasian women over a 6.5-year period. The researchers measured bone mass at the radius and observed 138 non-spinal fractures among 3,388 person-years of follow-up. The incidence of fracture was analyzed using a log-linear model, which showed that both age and decreasing radius bone mass increased the risk of fracture. Age was a stronger predictor of hip fractures, while midshaft radius bone mass was a stronger predictor of distal forearm fractures. The study concludes that bone mass is a useful predictor of fractures, but other age-related factors need to be identified to fully understand the risk factors for fractures. The findings provide evidence that bone mass and age have independent effects on fracture risk, with the risk increasing more significantly with age than with bone mass.This study investigates the relationship between bone mass and the risk of fracture in 521 Caucasian women over a 6.5-year period. The researchers measured bone mass at the radius and observed 138 non-spinal fractures among 3,388 person-years of follow-up. The incidence of fracture was analyzed using a log-linear model, which showed that both age and decreasing radius bone mass increased the risk of fracture. Age was a stronger predictor of hip fractures, while midshaft radius bone mass was a stronger predictor of distal forearm fractures. The study concludes that bone mass is a useful predictor of fractures, but other age-related factors need to be identified to fully understand the risk factors for fractures. The findings provide evidence that bone mass and age have independent effects on fracture risk, with the risk increasing more significantly with age than with bone mass.