The chapter discusses the role of software agents in e-commerce, highlighting their potential to revolutionize the buying and selling process. Agents are personalized, continuously running, and semi-autonomous, capable of automating time-consuming stages of the buying process. They can monitor inventory levels, collect and evaluate vendor and product information, negotiate terms, and place orders. The text also explores the use of agents as mediators in e-commerce, detailing their applications in need identification, product brokering, merchant brokering, and negotiation. Specific examples of agent systems, such as PersonaLogic, Firefly, and Tête-à-Tête, are discussed, along with their capabilities in filtering products, making recommendations, and facilitating negotiations. The chapter further delves into automated negotiation, where agents find and prepare contracts on behalf of their clients, and the benefits of using mobile agents in various applications, including e-commerce, personal assistance, secure brokering, and distributed information retrieval. Finally, it outlines future directions for agent-mediated e-commerce, emphasizing the need for standards to define goods, services, and payment mechanisms, and the potential for dynamic business partnerships created by agents.The chapter discusses the role of software agents in e-commerce, highlighting their potential to revolutionize the buying and selling process. Agents are personalized, continuously running, and semi-autonomous, capable of automating time-consuming stages of the buying process. They can monitor inventory levels, collect and evaluate vendor and product information, negotiate terms, and place orders. The text also explores the use of agents as mediators in e-commerce, detailing their applications in need identification, product brokering, merchant brokering, and negotiation. Specific examples of agent systems, such as PersonaLogic, Firefly, and Tête-à-Tête, are discussed, along with their capabilities in filtering products, making recommendations, and facilitating negotiations. The chapter further delves into automated negotiation, where agents find and prepare contracts on behalf of their clients, and the benefits of using mobile agents in various applications, including e-commerce, personal assistance, secure brokering, and distributed information retrieval. Finally, it outlines future directions for agent-mediated e-commerce, emphasizing the need for standards to define goods, services, and payment mechanisms, and the potential for dynamic business partnerships created by agents.