This paper presents an innovative infill wall design constructed from lightweight concrete reinforced with waste glass. The wall is designed to enhance fire resistance and robust performance under out-of-plane loading. Experimental and parametric studies were conducted to evaluate the wall's behavior under elevated temperatures and fire exposure. Key findings include: 1. **Weight Loss**: The weight loss of specimens increased with higher temperatures, peaking at 600 °C for specimens with 8% glass powder and decreasing at higher temperatures for specimens with 4% glass powder. 2. **Compressive Strength**: At lower temperatures, the addition of glass powder enhanced compressive strength, with 6% glass powder achieving the maximum strength at 600 °C. 3. **Tensile Strength**: Tensile strength was generally lower than compressive strength, with 8% glass powder showing the highest values. 4. **Fire Exposure**: The wall demonstrated excellent resistance to direct fire exposure, sustaining approximately one hour without significant cracking. 5. **Out-of-Plane Loading**: After exposure to 900 °C, the wall exhibited significant structural integrity, with a ultimate OOP strength of 18.81 kN and a weight-to-strength ratio of 11.17 times its weight. The optimal glass powder volume was determined to be 6%, and the wall's performance under fire and seismic conditions is expected to be superior. The study also provides equations to predict weight loss and compressive strength under different temperature conditions.This paper presents an innovative infill wall design constructed from lightweight concrete reinforced with waste glass. The wall is designed to enhance fire resistance and robust performance under out-of-plane loading. Experimental and parametric studies were conducted to evaluate the wall's behavior under elevated temperatures and fire exposure. Key findings include: 1. **Weight Loss**: The weight loss of specimens increased with higher temperatures, peaking at 600 °C for specimens with 8% glass powder and decreasing at higher temperatures for specimens with 4% glass powder. 2. **Compressive Strength**: At lower temperatures, the addition of glass powder enhanced compressive strength, with 6% glass powder achieving the maximum strength at 600 °C. 3. **Tensile Strength**: Tensile strength was generally lower than compressive strength, with 8% glass powder showing the highest values. 4. **Fire Exposure**: The wall demonstrated excellent resistance to direct fire exposure, sustaining approximately one hour without significant cracking. 5. **Out-of-Plane Loading**: After exposure to 900 °C, the wall exhibited significant structural integrity, with a ultimate OOP strength of 18.81 kN and a weight-to-strength ratio of 11.17 times its weight. The optimal glass powder volume was determined to be 6%, and the wall's performance under fire and seismic conditions is expected to be superior. The study also provides equations to predict weight loss and compressive strength under different temperature conditions.