When the life sciences get physical

When the life sciences get physical

June 2007 | Nigel Goldenfeld
The review discusses two recent books on systems biology: "An Introduction to Systems Biology: Design Principles of Biological Circuits" by Uri Alon and "Systems Biology: Properties of Reconstructed Networks" by Bernhard Ø. Palsson. Both books are well-written and provide different perspectives on systems biology. Alon's book is more accessible for physicists, focusing on key network motifs and their modeling with simple differential equations. It also addresses the question of whether physical principles underlie biological processes, including a chapter on robustness and kinetic proofreading. Palsson's book, on the other hand, focuses on techniques for reconstructing detailed biological models, emphasizing metabolic engineering and the use of models to drive discovery. The review highlights the importance of these books for quantitative scientists and physicists interested in modern biology. The review also discusses "The Cosmic Century: A History of Astrophysics and Cosmology" by Malcolm Longair, a timely and comprehensive account of the field. Longair, a respected physicist and researcher, provides an in-depth overview of the historical and theoretical developments in astrophysics and cosmology. The book covers the evolution of astronomy to astrophysics, the expansion of the electromagnetic spectrum in astronomical observations, and the advances in astrophysical cosmology over the past 50 years. The book is well-structured, with clear explanations and detailed appendices, making it a valuable resource for students, researchers, and lecturers. Longair's expertise in high-energy astrophysics and his contributions to major astronomical projects are highlighted. The book is praised for its clarity, depth, and engaging style, making it a significant contribution to the field.The review discusses two recent books on systems biology: "An Introduction to Systems Biology: Design Principles of Biological Circuits" by Uri Alon and "Systems Biology: Properties of Reconstructed Networks" by Bernhard Ø. Palsson. Both books are well-written and provide different perspectives on systems biology. Alon's book is more accessible for physicists, focusing on key network motifs and their modeling with simple differential equations. It also addresses the question of whether physical principles underlie biological processes, including a chapter on robustness and kinetic proofreading. Palsson's book, on the other hand, focuses on techniques for reconstructing detailed biological models, emphasizing metabolic engineering and the use of models to drive discovery. The review highlights the importance of these books for quantitative scientists and physicists interested in modern biology. The review also discusses "The Cosmic Century: A History of Astrophysics and Cosmology" by Malcolm Longair, a timely and comprehensive account of the field. Longair, a respected physicist and researcher, provides an in-depth overview of the historical and theoretical developments in astrophysics and cosmology. The book covers the evolution of astronomy to astrophysics, the expansion of the electromagnetic spectrum in astronomical observations, and the advances in astrophysical cosmology over the past 50 years. The book is well-structured, with clear explanations and detailed appendices, making it a valuable resource for students, researchers, and lecturers. Longair's expertise in high-energy astrophysics and his contributions to major astronomical projects are highlighted. The book is praised for its clarity, depth, and engaging style, making it a significant contribution to the field.
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