The ion-exchange properties of hydrotalcite-like compounds (HT) were investigated, focusing on their ability to exchange anions such as NO3⁻, Cl⁻, SO4²⁻, F⁻, Cl⁻, Br⁻, I⁻, OH⁻, SO4²⁻, CO3²⁻, and Naphthol Yellow S (NYS²⁻). The study determined ion-exchange isotherms and evaluated the selectivity of HT for these anions. The ion-exchange equilibrium constants for monovalent anions were found to follow the sequence OH⁻ > F⁻ > Cl⁻ > Br⁻ > NO3⁻ > I⁻, while for divalent anions, the sequence was CO3²⁻ > NYS²⁻ > SO4²⁻. The equilibrium constants increased with decreasing anion diameter, and the crystallite size in the 001 direction increased with higher anion selectivity. The OH-form of HT exhibited the smallest basal spacing and the largest crystallite size in the 001 direction. HT is a layered compound composed of positively charged brucite-like layers alternating with negatively charged interlayers. It is stable up to 400°C but transforms into a MgO-Al2O3 solid solution at higher temperatures. HT and its heat-treated form can capture anions and are useful as halogen scavengers and thermal stabilizers. The study synthesized HT in the NO3⁻, Cl⁻, and SO4²⁻ forms and determined their ion-exchange isotherms and selectivity for various anions. X-ray powder diffraction analyses were conducted to measure the basal spacing and reflection width of HT as a function of composition. The results showed that the basal spacing decreased with increasing anion selectivity, and the crystallite size increased with higher selectivity. The HT-NO3 system had a larger basal spacing than expected, possibly due to repulsion between NO3⁻ ions. The HT-OH system had the smallest basal spacing and largest crystallite size among the studied anion forms. The study concluded that HT is a promising anion exchanger with high capacity and unique ion selectivity. It can be used for removing acid dyes and various anions from wastewater, as well as for neutralizing and stabilizing halogen-containing polymers. The ion-exchange properties of HT are influenced by the size and selectivity of the anions, making it a valuable material for various applications.The ion-exchange properties of hydrotalcite-like compounds (HT) were investigated, focusing on their ability to exchange anions such as NO3⁻, Cl⁻, SO4²⁻, F⁻, Cl⁻, Br⁻, I⁻, OH⁻, SO4²⁻, CO3²⁻, and Naphthol Yellow S (NYS²⁻). The study determined ion-exchange isotherms and evaluated the selectivity of HT for these anions. The ion-exchange equilibrium constants for monovalent anions were found to follow the sequence OH⁻ > F⁻ > Cl⁻ > Br⁻ > NO3⁻ > I⁻, while for divalent anions, the sequence was CO3²⁻ > NYS²⁻ > SO4²⁻. The equilibrium constants increased with decreasing anion diameter, and the crystallite size in the 001 direction increased with higher anion selectivity. The OH-form of HT exhibited the smallest basal spacing and the largest crystallite size in the 001 direction. HT is a layered compound composed of positively charged brucite-like layers alternating with negatively charged interlayers. It is stable up to 400°C but transforms into a MgO-Al2O3 solid solution at higher temperatures. HT and its heat-treated form can capture anions and are useful as halogen scavengers and thermal stabilizers. The study synthesized HT in the NO3⁻, Cl⁻, and SO4²⁻ forms and determined their ion-exchange isotherms and selectivity for various anions. X-ray powder diffraction analyses were conducted to measure the basal spacing and reflection width of HT as a function of composition. The results showed that the basal spacing decreased with increasing anion selectivity, and the crystallite size increased with higher selectivity. The HT-NO3 system had a larger basal spacing than expected, possibly due to repulsion between NO3⁻ ions. The HT-OH system had the smallest basal spacing and largest crystallite size among the studied anion forms. The study concluded that HT is a promising anion exchanger with high capacity and unique ion selectivity. It can be used for removing acid dyes and various anions from wastewater, as well as for neutralizing and stabilizing halogen-containing polymers. The ion-exchange properties of HT are influenced by the size and selectivity of the anions, making it a valuable material for various applications.