This review provides an overview of current research and progress in antiaging strategies and treatments. Aging is characterized by a gradual loss of physiological fitness and the accumulation of cellular damage, leading to deteriorated functions and increased vulnerability to diseases. Antiaging research has a long history, with various strategies developed to promote healthy aging and extend lifespan, including lifestyle adjustments, medical treatments, and social programs. The review analyzes recent research publications from the CAS Content Collection to examine the publication landscape of antiaging strategies and treatments, highlighting trends in research progress across time, geography, and development pipelines. It assesses current antiaging approaches and explores their correlations with age-related diseases. The review also summarizes well-known and currently evaluated antiaging agents and reviews clinical applications of antiaging products with their development pipelines. The review discusses various antiaging strategies, including parabiosis, metabolic manipulation, senotherapy, cellular reprogramming, telomere reactivation, hormesis, hormonal replacement, prebiotic/probiotics and fecal transplantation, caloric restriction/intermittent fasting, physical exercise, stem cell therapy, and dietary supplementation. Each strategy is examined in terms of its mechanisms, potential benefits, and challenges. The review also highlights the importance of autophagy enhancement and brain antiaging strategies, emphasizing the role of exercise in maintaining brain health and delaying aging. The review provides insights into the global research landscape of antiaging strategies, based on data from the CAS Content Collection. It highlights the significant contributions of researchers from China, the United States, Japan, and South Korea. The review also discusses the flow of patent filings related to aging mechanisms and antiaging strategies, emphasizing the importance of patent protection and the distribution of patent filings across different jurisdictions. Overall, the review aims to summarize current knowledge on preventive strategies and treatment remedies in the field of aging, outline challenges, and evaluate growth opportunities to further efforts to solve remaining problems.This review provides an overview of current research and progress in antiaging strategies and treatments. Aging is characterized by a gradual loss of physiological fitness and the accumulation of cellular damage, leading to deteriorated functions and increased vulnerability to diseases. Antiaging research has a long history, with various strategies developed to promote healthy aging and extend lifespan, including lifestyle adjustments, medical treatments, and social programs. The review analyzes recent research publications from the CAS Content Collection to examine the publication landscape of antiaging strategies and treatments, highlighting trends in research progress across time, geography, and development pipelines. It assesses current antiaging approaches and explores their correlations with age-related diseases. The review also summarizes well-known and currently evaluated antiaging agents and reviews clinical applications of antiaging products with their development pipelines. The review discusses various antiaging strategies, including parabiosis, metabolic manipulation, senotherapy, cellular reprogramming, telomere reactivation, hormesis, hormonal replacement, prebiotic/probiotics and fecal transplantation, caloric restriction/intermittent fasting, physical exercise, stem cell therapy, and dietary supplementation. Each strategy is examined in terms of its mechanisms, potential benefits, and challenges. The review also highlights the importance of autophagy enhancement and brain antiaging strategies, emphasizing the role of exercise in maintaining brain health and delaying aging. The review provides insights into the global research landscape of antiaging strategies, based on data from the CAS Content Collection. It highlights the significant contributions of researchers from China, the United States, Japan, and South Korea. The review also discusses the flow of patent filings related to aging mechanisms and antiaging strategies, emphasizing the importance of patent protection and the distribution of patent filings across different jurisdictions. Overall, the review aims to summarize current knowledge on preventive strategies and treatment remedies in the field of aging, outline challenges, and evaluate growth opportunities to further efforts to solve remaining problems.