The article "Antimicrobial Activities of Natural Bioactive Polyphenols" by Manas Kumar Mandal and Abraham J. Domb reviews the antimicrobial properties of polyphenols, which are secondary metabolites found in plants. These polyphenols, including phenolic acids, flavonoids, and non-flavonoids, have a wide range of biological functions and are used in various products such as food, beauty, dietary supplements, and medicines. The authors discuss the sources, classes, and subclasses of polyphenols, highlighting their benefits such as antiallergic, antioxidant, anticancer, anti-inflammatory, and antihypertensive properties. They also explore the antimicrobial activities of different polyphenols, including their mechanisms of action, such as disrupting cell membranes, inhibiting enzyme activities, and producing reactive oxygen species. The review covers the antimicrobial effects of polyphenols against bacteria, fungi, and viruses, and their potential applications in treating infectious diseases. The authors emphasize the need for reliable scientific research to ensure the safety and effectiveness of polyphenols as antimicrobial agents. They conclude by discussing future prospects, including the need to improve the solubility and delivery systems of polyphenols to enhance their antimicrobial efficacy.The article "Antimicrobial Activities of Natural Bioactive Polyphenols" by Manas Kumar Mandal and Abraham J. Domb reviews the antimicrobial properties of polyphenols, which are secondary metabolites found in plants. These polyphenols, including phenolic acids, flavonoids, and non-flavonoids, have a wide range of biological functions and are used in various products such as food, beauty, dietary supplements, and medicines. The authors discuss the sources, classes, and subclasses of polyphenols, highlighting their benefits such as antiallergic, antioxidant, anticancer, anti-inflammatory, and antihypertensive properties. They also explore the antimicrobial activities of different polyphenols, including their mechanisms of action, such as disrupting cell membranes, inhibiting enzyme activities, and producing reactive oxygen species. The review covers the antimicrobial effects of polyphenols against bacteria, fungi, and viruses, and their potential applications in treating infectious diseases. The authors emphasize the need for reliable scientific research to ensure the safety and effectiveness of polyphenols as antimicrobial agents. They conclude by discussing future prospects, including the need to improve the solubility and delivery systems of polyphenols to enhance their antimicrobial efficacy.