The article reviews the antimicrobial and other pharmacological properties of *Ocimum basilicum* (basil), a plant belonging to the Lamiaceae family. Basil contains a variety of bioactive phytochemicals, including alkaloids, phenolics, flavonoids, tannins, saponins, reducing sugars, cardiac glycosides, steroids, and glycosides. These compounds give basil several therapeutic effects, such as anti-inflammatory, antifungal, antibacterial, antioxidant, and wound healing properties. The plant's extracts have been shown to exhibit excellent potential as medicinal raw materials due to their non-toxic nature and numerous health benefits. The review covers the following key areas: 1. **Antimicrobial Activity**: Basil extracts have demonstrated strong antibacterial activity against various bacterial species, including *Staphylococcus aureus* and *Escherichia coli*. The antibacterial effects are attributed to the presence of phenolic compounds like eugenol and monoterpenoid compounds like linalool. 2. **Antifungal Activity**: Basil extracts have shown significant antifungal activity against several fungal strains, including *Fusarium oxysporum* and *Candida albicans*. The antifungal properties are linked to the presence of tannins, which can inhibit microbial protein and nutrient absorption. 3. **Antioxidant Activity**: Basil extracts have comparable or superior antioxidant activity compared to synthetic antioxidants like BHA and BHT. The antioxidant effects are associated with the presence of phenolic compounds, flavonoids, and tannins. 4. **Anti-Inflammatory Activity**: Basil extracts have been effective in reducing inflammation in various models, including paw edema, vascular permeability, granulomatous inflammation, and peritonitis. The anti-inflammatory effects are attributed to the presence of flavonoids, tannins, and other phytochemicals. 5. **Wound Healing**: Basil extracts have been shown to promote wound healing in both in vitro and in vivo studies. The extracts have increased epithelialization and angiogenesis, leading to faster wound closure. 6. **Antiviral Activity**: Basil extracts and purified components have demonstrated antiviral activity against RNA and DNA viruses, including *Enterovirus 71*, *Coxackievirus B1*, *Hepatitis B virus*, *Adenoviruses*, and *Herpes viruses*. The antiviral mechanisms are linked to the presence of compounds like apigenin, ursolic acid, and linalool. The review highlights the broad range of therapeutic capacities of *Ocimum basilicum* and its potential as a natural source of medicinal compounds.The article reviews the antimicrobial and other pharmacological properties of *Ocimum basilicum* (basil), a plant belonging to the Lamiaceae family. Basil contains a variety of bioactive phytochemicals, including alkaloids, phenolics, flavonoids, tannins, saponins, reducing sugars, cardiac glycosides, steroids, and glycosides. These compounds give basil several therapeutic effects, such as anti-inflammatory, antifungal, antibacterial, antioxidant, and wound healing properties. The plant's extracts have been shown to exhibit excellent potential as medicinal raw materials due to their non-toxic nature and numerous health benefits. The review covers the following key areas: 1. **Antimicrobial Activity**: Basil extracts have demonstrated strong antibacterial activity against various bacterial species, including *Staphylococcus aureus* and *Escherichia coli*. The antibacterial effects are attributed to the presence of phenolic compounds like eugenol and monoterpenoid compounds like linalool. 2. **Antifungal Activity**: Basil extracts have shown significant antifungal activity against several fungal strains, including *Fusarium oxysporum* and *Candida albicans*. The antifungal properties are linked to the presence of tannins, which can inhibit microbial protein and nutrient absorption. 3. **Antioxidant Activity**: Basil extracts have comparable or superior antioxidant activity compared to synthetic antioxidants like BHA and BHT. The antioxidant effects are associated with the presence of phenolic compounds, flavonoids, and tannins. 4. **Anti-Inflammatory Activity**: Basil extracts have been effective in reducing inflammation in various models, including paw edema, vascular permeability, granulomatous inflammation, and peritonitis. The anti-inflammatory effects are attributed to the presence of flavonoids, tannins, and other phytochemicals. 5. **Wound Healing**: Basil extracts have been shown to promote wound healing in both in vitro and in vivo studies. The extracts have increased epithelialization and angiogenesis, leading to faster wound closure. 6. **Antiviral Activity**: Basil extracts and purified components have demonstrated antiviral activity against RNA and DNA viruses, including *Enterovirus 71*, *Coxackievirus B1*, *Hepatitis B virus*, *Adenoviruses*, and *Herpes viruses*. The antiviral mechanisms are linked to the presence of compounds like apigenin, ursolic acid, and linalool. The review highlights the broad range of therapeutic capacities of *Ocimum basilicum* and its potential as a natural source of medicinal compounds.