This paper aims to synthesize empirical findings on Antonovsky's sense of coherence (SOC) and its relationship with health. The study is descriptive and analytical, integrating contemporary knowledge from salutogenic research published between 1992 and 2003. The review includes 458 scientific publications and 13 doctoral theses from various countries. The main results show that SOC is strongly related to perceived health, particularly mental health. The stronger the SOC, the better the perceived health, regardless of age, sex, ethnicity, or nationality. SOC appears to have a main, moderating, or mediating role in explaining health, and it can predict health outcomes. However, SOC alone does not fully explain overall health. The paper concludes that SOC is a valuable health-promoting resource, strengthening resilience and fostering a positive subjective state of health. The salutogenic approach is recommended for more extensive implementation in health promotion and public health research.This paper aims to synthesize empirical findings on Antonovsky's sense of coherence (SOC) and its relationship with health. The study is descriptive and analytical, integrating contemporary knowledge from salutogenic research published between 1992 and 2003. The review includes 458 scientific publications and 13 doctoral theses from various countries. The main results show that SOC is strongly related to perceived health, particularly mental health. The stronger the SOC, the better the perceived health, regardless of age, sex, ethnicity, or nationality. SOC appears to have a main, moderating, or mediating role in explaining health, and it can predict health outcomes. However, SOC alone does not fully explain overall health. The paper concludes that SOC is a valuable health-promoting resource, strengthening resilience and fostering a positive subjective state of health. The salutogenic approach is recommended for more extensive implementation in health promotion and public health research.