2011 February 22; 57(8): 891–903. | Mewton Nathan, MD PhD1,2, Liu Chia Ying, PhD1, Croisille Pierre, MD PhD2, Bluemke David, MD PhD1,3, and Lima João, AC, MD MBA1
This review discusses the assessment of myocardial fibrosis using cardiac magnetic resonance (CMR). Myocardial fibrosis, a common feature in various cardiomyopathies, leads to impaired cardiac function and adverse cardiovascular events. CMR, particularly with late gadolinium enhancement (LGE) and T1 mapping, has emerged as a valuable tool for characterizing the extent and type of fibrosis. LGE allows for the non-invasive detection of myocardial fibrosis, while T1 mapping provides more detailed information on tissue composition. The review highlights the advantages and limitations of these techniques, emphasizing their potential in monitoring and therapeutic management of patients with cardiomyopathies. Despite the promise of these techniques, further research is needed to standardize their use and validate their clinical utility.This review discusses the assessment of myocardial fibrosis using cardiac magnetic resonance (CMR). Myocardial fibrosis, a common feature in various cardiomyopathies, leads to impaired cardiac function and adverse cardiovascular events. CMR, particularly with late gadolinium enhancement (LGE) and T1 mapping, has emerged as a valuable tool for characterizing the extent and type of fibrosis. LGE allows for the non-invasive detection of myocardial fibrosis, while T1 mapping provides more detailed information on tissue composition. The review highlights the advantages and limitations of these techniques, emphasizing their potential in monitoring and therapeutic management of patients with cardiomyopathies. Despite the promise of these techniques, further research is needed to standardize their use and validate their clinical utility.