This study investigates the association between exposure to 6PPD-quinone and children's BMI, influenza, and diarrhea in an e-waste recycling town (Guiyu) compared to a reference area (Haojiang). 183 dust samples were collected from roads, homes, and kindergartens in both areas between 2019 and 2021. 6PPD-quinone concentrations in kindergarten and house dust from the e-waste exposed group were significantly higher than those from the reference group. Children in the exposed group had a higher exposure risk to 6PPD-quinone than the reference group. A higher daily intake of 6PPD-quinone from kindergarten dust was associated with a lower BMI and a higher frequency of influenza and diarrhea in children. The study found that e-waste may be another potential source of 6PPD-quinone, in addition to rubber tires. The study also found that 6PPD-quinone exposure was associated with decreased BMI in children, increased frequency of influenza, and increased frequency of diarrhea. The study highlights the potential health risks of 6PPD-quinone exposure to children in e-waste recycling areas.This study investigates the association between exposure to 6PPD-quinone and children's BMI, influenza, and diarrhea in an e-waste recycling town (Guiyu) compared to a reference area (Haojiang). 183 dust samples were collected from roads, homes, and kindergartens in both areas between 2019 and 2021. 6PPD-quinone concentrations in kindergarten and house dust from the e-waste exposed group were significantly higher than those from the reference group. Children in the exposed group had a higher exposure risk to 6PPD-quinone than the reference group. A higher daily intake of 6PPD-quinone from kindergarten dust was associated with a lower BMI and a higher frequency of influenza and diarrhea in children. The study found that e-waste may be another potential source of 6PPD-quinone, in addition to rubber tires. The study also found that 6PPD-quinone exposure was associated with decreased BMI in children, increased frequency of influenza, and increased frequency of diarrhea. The study highlights the potential health risks of 6PPD-quinone exposure to children in e-waste recycling areas.