This study, conducted in East London, aimed to examine the social, economic, and behavioral characteristics of patients with HIV infection currently receiving treatment and care in hospitals. The research focused on ethnicity, gender, sexuality, education, employment, housing, HIV treatment, stigma, discrimination, religion, migration, and sexual risk behavior. The study involved 2680 patients attending outpatient clinics at six hospitals in East London over a 4-6 month period, with 1687 completing a questionnaire. The response rate was 73% among eligible patients and 63% overall. The findings provide valuable information for planning and delivering appropriate clinical care, social support, and health promotion for people living with HIV in East London and potentially elsewhere in the UK. The study highlights the changing epidemiological pattern of HIV in the UK, particularly in East London due to its ethnically diverse population.This study, conducted in East London, aimed to examine the social, economic, and behavioral characteristics of patients with HIV infection currently receiving treatment and care in hospitals. The research focused on ethnicity, gender, sexuality, education, employment, housing, HIV treatment, stigma, discrimination, religion, migration, and sexual risk behavior. The study involved 2680 patients attending outpatient clinics at six hospitals in East London over a 4-6 month period, with 1687 completing a questionnaire. The response rate was 73% among eligible patients and 63% overall. The findings provide valuable information for planning and delivering appropriate clinical care, social support, and health promotion for people living with HIV in East London and potentially elsewhere in the UK. The study highlights the changing epidemiological pattern of HIV in the UK, particularly in East London due to its ethnically diverse population.