This systematic review examines the potential of bioactive-glass-based materials in accelerating diabetic wound healing. Diabetes affects a significant global population, with 537 million adults affected in 2021, and the associated healthcare costs reaching USD 966 billion. Diabetic foot ulcers (DFUs) are a common complication, affecting around 15% of diabetic patients and often leading to severe complications if left untreated. The review highlights that bioactive glass (BG) materials show promising results in enhancing wound healing by activating fibroblasts, promoting angiogenesis, and improving collagen deposition. The materials are categorized into hydrogels, electrospun fibers, and miscellaneous forms, including ointments, extracts, and composites. In vitro studies demonstrate that BG-based materials enhance cell viability, angiogenesis, and antimicrobial properties. In vivo studies using animal models show improved wound closure, reduced inflammation, and better collagen organization. The review concludes that the addition of BG to wound dressings is valuable for accelerating and improving the quality of diabetic wound healing, contributing to the development of therapeutic strategies for this condition.This systematic review examines the potential of bioactive-glass-based materials in accelerating diabetic wound healing. Diabetes affects a significant global population, with 537 million adults affected in 2021, and the associated healthcare costs reaching USD 966 billion. Diabetic foot ulcers (DFUs) are a common complication, affecting around 15% of diabetic patients and often leading to severe complications if left untreated. The review highlights that bioactive glass (BG) materials show promising results in enhancing wound healing by activating fibroblasts, promoting angiogenesis, and improving collagen deposition. The materials are categorized into hydrogels, electrospun fibers, and miscellaneous forms, including ointments, extracts, and composites. In vitro studies demonstrate that BG-based materials enhance cell viability, angiogenesis, and antimicrobial properties. In vivo studies using animal models show improved wound closure, reduced inflammation, and better collagen organization. The review concludes that the addition of BG to wound dressings is valuable for accelerating and improving the quality of diabetic wound healing, contributing to the development of therapeutic strategies for this condition.