This review explores the potential of bioactive peptides derived from natural sources as an alternative therapeutic approach for cancer management. Bioactive peptides, obtained from plant and animal sources, have shown promise in enhancing the efficacy of conventional cancer therapies and reducing adverse side effects. The review highlights the anticancer, anti-invasion, and immunomodulatory properties of these peptides. Peptides from common beans, chickpeas, wheat germ, and mung beans have demonstrated antiproliferative and toxic effects on cancer cells, while marine peptides have shown potential in inhibiting tumor growth and metastasis. The review also discusses the immunomodulatory activities of bioactive peptides, including their ability to enhance immune responses and modulate the immune system. Key findings include the effectiveness of peptides in inducing apoptosis, cell cycle arrest, and reducing angiogenesis. Additionally, the review emphasizes the need for further research to fully characterize the clinical potential of these bioactive peptides.This review explores the potential of bioactive peptides derived from natural sources as an alternative therapeutic approach for cancer management. Bioactive peptides, obtained from plant and animal sources, have shown promise in enhancing the efficacy of conventional cancer therapies and reducing adverse side effects. The review highlights the anticancer, anti-invasion, and immunomodulatory properties of these peptides. Peptides from common beans, chickpeas, wheat germ, and mung beans have demonstrated antiproliferative and toxic effects on cancer cells, while marine peptides have shown potential in inhibiting tumor growth and metastasis. The review also discusses the immunomodulatory activities of bioactive peptides, including their ability to enhance immune responses and modulate the immune system. Key findings include the effectiveness of peptides in inducing apoptosis, cell cycle arrest, and reducing angiogenesis. Additionally, the review emphasizes the need for further research to fully characterize the clinical potential of these bioactive peptides.