The chapter discusses the biological control of soilborne plant pathogens using bacteria in the rhizosphere. It highlights the historical development of this field, emphasizing the increased interest and research in recent decades due to concerns about chemical pesticides. The rhizosphere is identified as a critical environment for biological control, where microorganisms can prevent pathogen infection before and during primary and secondary stages of infection. The review covers various bacterial species with potential for biocontrol, including *Agrobacterium*, *Bacillus*, and *Pseudomonas*. It also discusses the mechanisms by which these bacteria suppress pathogens, such as substrate competition, niche exclusion, siderophore production, and antibiotic production. The chapter addresses the challenges in selecting effective strains for field application and the importance of root colonization by introduced bacteria. It concludes by discussing the prospects for future research and commercial development of bacterial biocontrol agents.The chapter discusses the biological control of soilborne plant pathogens using bacteria in the rhizosphere. It highlights the historical development of this field, emphasizing the increased interest and research in recent decades due to concerns about chemical pesticides. The rhizosphere is identified as a critical environment for biological control, where microorganisms can prevent pathogen infection before and during primary and secondary stages of infection. The review covers various bacterial species with potential for biocontrol, including *Agrobacterium*, *Bacillus*, and *Pseudomonas*. It also discusses the mechanisms by which these bacteria suppress pathogens, such as substrate competition, niche exclusion, siderophore production, and antibiotic production. The chapter addresses the challenges in selecting effective strains for field application and the importance of root colonization by introduced bacteria. It concludes by discussing the prospects for future research and commercial development of bacterial biocontrol agents.