Peri-implantitis is a bacterial infection that causes soft tissue inflammation and alveolar bone resorption, leading to implant failure. Dental implants lack antibacterial properties, and bacterial colonization and biofilm formation are major causes of peri-implantitis. Current research focuses on improving the antibacterial properties of dental implants through surface modification, such as micro-nano surface textures, functional coatings, and materials with intrinsic antibacterial properties. These surfaces can incorporate bioactive molecules, metallic nanoparticles, or other functional components to enhance osteogenic properties and accelerate healing. This review summarizes recent developments in biomaterial science and surface engineering strategies for dental implants to inhibit biofilm formation and promote bone-implant integration. It also discusses challenges in translating laboratory research to clinical applications and proposes future research directions. Peri-implantitis is a significant threat to implant success, with high prevalence rates and a need for effective prevention and treatment. Current treatment strategies include mechanical debridement and antibiotic therapy, but these may not fully address the issue. The review highlights the importance of balancing antibacterial efficacy, biological safety, and osteogenic properties in dental implants. Various strategies, including surface modification with antibacterial agents, metal and metal oxide coatings, and graphene-based materials, are discussed to enhance the antibacterial and osteogenic properties of dental implants. The review also emphasizes the need for further research to evaluate the long-term safety and effectiveness of these strategies in clinical settings.Peri-implantitis is a bacterial infection that causes soft tissue inflammation and alveolar bone resorption, leading to implant failure. Dental implants lack antibacterial properties, and bacterial colonization and biofilm formation are major causes of peri-implantitis. Current research focuses on improving the antibacterial properties of dental implants through surface modification, such as micro-nano surface textures, functional coatings, and materials with intrinsic antibacterial properties. These surfaces can incorporate bioactive molecules, metallic nanoparticles, or other functional components to enhance osteogenic properties and accelerate healing. This review summarizes recent developments in biomaterial science and surface engineering strategies for dental implants to inhibit biofilm formation and promote bone-implant integration. It also discusses challenges in translating laboratory research to clinical applications and proposes future research directions. Peri-implantitis is a significant threat to implant success, with high prevalence rates and a need for effective prevention and treatment. Current treatment strategies include mechanical debridement and antibiotic therapy, but these may not fully address the issue. The review highlights the importance of balancing antibacterial efficacy, biological safety, and osteogenic properties in dental implants. Various strategies, including surface modification with antibacterial agents, metal and metal oxide coatings, and graphene-based materials, are discussed to enhance the antibacterial and osteogenic properties of dental implants. The review also emphasizes the need for further research to evaluate the long-term safety and effectiveness of these strategies in clinical settings.