Silver nanoparticles (AgNPs) have gained significant attention in biomedical applications due to their unique physicochemical properties and broad antimicrobial activity. This review summarizes the latest research on AgNPs, focusing on their potential in drug delivery, wound healing, catheter modification, dental applications, bone healing, and other medical fields. AgNPs are effective antimicrobial agents that can be used in various biomedical applications, including wound dressings, tissue scaffolds, and medical devices. They are also used in drug delivery systems to enhance the therapeutic effects of anticancer drugs and other medications. AgNPs have shown promising results in preventing infections associated with catheters and in dental applications for preventing caries and promoting oral health. However, their use is accompanied by concerns regarding their toxicity and potential side effects. The review highlights the importance of understanding the physicochemical properties of AgNPs, their interactions with biological systems, and their potential toxic effects. The study also emphasizes the need for further research to ensure the safe and effective use of AgNPs in biomedical applications. Overall, AgNPs represent a promising area of research with significant potential for improving healthcare outcomes.Silver nanoparticles (AgNPs) have gained significant attention in biomedical applications due to their unique physicochemical properties and broad antimicrobial activity. This review summarizes the latest research on AgNPs, focusing on their potential in drug delivery, wound healing, catheter modification, dental applications, bone healing, and other medical fields. AgNPs are effective antimicrobial agents that can be used in various biomedical applications, including wound dressings, tissue scaffolds, and medical devices. They are also used in drug delivery systems to enhance the therapeutic effects of anticancer drugs and other medications. AgNPs have shown promising results in preventing infections associated with catheters and in dental applications for preventing caries and promoting oral health. However, their use is accompanied by concerns regarding their toxicity and potential side effects. The review highlights the importance of understanding the physicochemical properties of AgNPs, their interactions with biological systems, and their potential toxic effects. The study also emphasizes the need for further research to ensure the safe and effective use of AgNPs in biomedical applications. Overall, AgNPs represent a promising area of research with significant potential for improving healthcare outcomes.