This study explores the development and testing of a biomimetic neurostimulation framework to enhance naturalistic touch sensations in individuals with sensorimotor deficits. The framework is designed to "write" physiologically plausible information back into the peripheral nervous system, inspired by natural touch coding. Using a computational model (FootSim) that emulates the spatio-temporal dynamics of natural touch, the researchers developed biomimetic stimulation policies. These policies were experimentally assessed in cats and then implemented in a clinical trial with transfemoral amputees. The results showed that biomimetic neurostimulation improved mobility and reduced mental effort compared to traditional approaches. The study highlights the potential of biomimetic approaches in advancing assistive neurotechnologies, particularly in restoring natural sensory experiences and improving functional outcomes for individuals with disabilities.This study explores the development and testing of a biomimetic neurostimulation framework to enhance naturalistic touch sensations in individuals with sensorimotor deficits. The framework is designed to "write" physiologically plausible information back into the peripheral nervous system, inspired by natural touch coding. Using a computational model (FootSim) that emulates the spatio-temporal dynamics of natural touch, the researchers developed biomimetic stimulation policies. These policies were experimentally assessed in cats and then implemented in a clinical trial with transfemoral amputees. The results showed that biomimetic neurostimulation improved mobility and reduced mental effort compared to traditional approaches. The study highlights the potential of biomimetic approaches in advancing assistive neurotechnologies, particularly in restoring natural sensory experiences and improving functional outcomes for individuals with disabilities.