A meta-analysis of clinical data from 1994 COVID-19 patients (December 2019–February 2020) revealed key characteristics, discharge, and fatality rates. The most common symptoms were fever (88.5%), cough (68.6%), myalgia/fatigue (35.8%), expectoration (28.2%), and dyspnea (21.9%). Minor symptoms included headache/dizziness (12.1%), diarrhea (4.8%), and nausea/vomiting (3.9%). Laboratory findings showed lymphocytopenia (64.5%), elevated CRP (44.3%), elevated LDH (28.3%), and leukocytopenia (29.4%). The single-arm meta-analysis found that 60% of patients were male, the discharge rate was 52% (95% CI [0.34, 0.70]), and the fatality rate was 5% (95% CI [0.01, 0.11]). The study included 10 articles, with data from 1995 patients. The results showed no significant publication bias. The study highlights the importance of early identification and management of suspected cases to control the spread of the virus. The findings suggest that while the fatality rate of COVID-19 is lower than that of SARS and MERS, certain risk factors such as advanced age, cancer, and underlying diseases increase the risk of mortality. The study also emphasizes the need for further research to confirm the clinical utility of laboratory indicators and to improve diagnostic and treatment strategies. The results provide valuable insights for clinical management and public health response to the pandemic.A meta-analysis of clinical data from 1994 COVID-19 patients (December 2019–February 2020) revealed key characteristics, discharge, and fatality rates. The most common symptoms were fever (88.5%), cough (68.6%), myalgia/fatigue (35.8%), expectoration (28.2%), and dyspnea (21.9%). Minor symptoms included headache/dizziness (12.1%), diarrhea (4.8%), and nausea/vomiting (3.9%). Laboratory findings showed lymphocytopenia (64.5%), elevated CRP (44.3%), elevated LDH (28.3%), and leukocytopenia (29.4%). The single-arm meta-analysis found that 60% of patients were male, the discharge rate was 52% (95% CI [0.34, 0.70]), and the fatality rate was 5% (95% CI [0.01, 0.11]). The study included 10 articles, with data from 1995 patients. The results showed no significant publication bias. The study highlights the importance of early identification and management of suspected cases to control the spread of the virus. The findings suggest that while the fatality rate of COVID-19 is lower than that of SARS and MERS, certain risk factors such as advanced age, cancer, and underlying diseases increase the risk of mortality. The study also emphasizes the need for further research to confirm the clinical utility of laboratory indicators and to improve diagnostic and treatment strategies. The results provide valuable insights for clinical management and public health response to the pandemic.