CT Imaging Features of 2019 Novel Coronavirus (2019-nCoV)

CT Imaging Features of 2019 Novel Coronavirus (2019-nCoV)

Received January 28, 2020; revision requested and received January 31; accepted February 3. | Michael Chung, MD • Adam Bernheim, MD • Xueyan Mei, MS • Ning Zhang, MD • Mingqian Huang, MD • Xianjun Zeng, MD • Jiufa Cui, MD • Wenjian Xu, MD • Yang Yang, PhD • Zabi A. Fayad, PhD • Adam Jacobi, MD • Kunwei Li, MD • Shaolin Li, MD • Hong Shan, MD
This retrospective case series reviews chest CT scans of 21 symptomatic patients from China infected with the 2019 novel coronavirus (2019-nCoV). The study highlights typical CT findings, including bilateral pulmonary ground-glass and consolidative opacities, often with a rounded morphology and peripheral lung distribution. Notably, lung cavitation, discrete pulmonary nodules, pleural effusions, and lymphadenopathy were absent. Follow-up imaging in a subset of patients showed mild to moderate progression of disease, characterized by increasing extent and density of lung opacities. The findings are similar to those seen in previous coronavirus outbreaks, such as SARS and MERS, but with a higher likelihood of multifocal involvement. The study emphasizes the importance of early recognition and diagnosis through chest CT imaging to facilitate timely treatment and public health response.This retrospective case series reviews chest CT scans of 21 symptomatic patients from China infected with the 2019 novel coronavirus (2019-nCoV). The study highlights typical CT findings, including bilateral pulmonary ground-glass and consolidative opacities, often with a rounded morphology and peripheral lung distribution. Notably, lung cavitation, discrete pulmonary nodules, pleural effusions, and lymphadenopathy were absent. Follow-up imaging in a subset of patients showed mild to moderate progression of disease, characterized by increasing extent and density of lung opacities. The findings are similar to those seen in previous coronavirus outbreaks, such as SARS and MERS, but with a higher likelihood of multifocal involvement. The study emphasizes the importance of early recognition and diagnosis through chest CT imaging to facilitate timely treatment and public health response.
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