The rapid urbanization and digital transformation of African cities have led to the emergence of Smart Cities, integrating advanced technologies to enhance urban efficiency and sustainability. However, this digital transformation has also introduced significant cybersecurity challenges, particularly in interconnected urban environments. This paper examines the cybersecurity challenges faced by African metropolises, focusing on case studies of Johannesburg, Nairobi, Lagos, and Cairo. These cities, as examples of global urbanization trends, are adopting Smart City initiatives to address urban challenges and promote economic development. While Smart Cities offer improved services and connectivity, they also expose cities to a wide range of cybersecurity threats, including data breaches, infrastructure disruptions, and vulnerabilities in critical systems such as energy grids, transportation, and healthcare networks. The interconnected nature of Smart City technologies creates a vast attack surface, making them susceptible to cyber-attacks. The paper highlights the socio-economic implications of these threats, emphasizing the need for resilient cybersecurity frameworks to protect citizen data and urban functionality. It also discusses the importance of comprehensive cybersecurity strategies tailored to the unique challenges of African Smart Cities. The case review reveals that many African cities face challenges such as insufficient investment in cybersecurity infrastructure, rapid technological adoption without proper planning, and a lack of standardized security protocols. These factors contribute to vulnerabilities in Smart City systems. The paper recommends collaborative efforts among governments, the private sector, and cybersecurity experts to develop robust cybersecurity strategies. It emphasizes the need for public awareness, international collaboration, and the integration of cybersecurity into the design phase of Smart City projects. The findings underscore the urgency for immediate investments, policy revisions, and collaborative efforts to strengthen the cybersecurity resilience of African Smart Cities. The paper concludes that addressing these challenges is essential for the successful and sustainable development of Smart Cities in Africa.The rapid urbanization and digital transformation of African cities have led to the emergence of Smart Cities, integrating advanced technologies to enhance urban efficiency and sustainability. However, this digital transformation has also introduced significant cybersecurity challenges, particularly in interconnected urban environments. This paper examines the cybersecurity challenges faced by African metropolises, focusing on case studies of Johannesburg, Nairobi, Lagos, and Cairo. These cities, as examples of global urbanization trends, are adopting Smart City initiatives to address urban challenges and promote economic development. While Smart Cities offer improved services and connectivity, they also expose cities to a wide range of cybersecurity threats, including data breaches, infrastructure disruptions, and vulnerabilities in critical systems such as energy grids, transportation, and healthcare networks. The interconnected nature of Smart City technologies creates a vast attack surface, making them susceptible to cyber-attacks. The paper highlights the socio-economic implications of these threats, emphasizing the need for resilient cybersecurity frameworks to protect citizen data and urban functionality. It also discusses the importance of comprehensive cybersecurity strategies tailored to the unique challenges of African Smart Cities. The case review reveals that many African cities face challenges such as insufficient investment in cybersecurity infrastructure, rapid technological adoption without proper planning, and a lack of standardized security protocols. These factors contribute to vulnerabilities in Smart City systems. The paper recommends collaborative efforts among governments, the private sector, and cybersecurity experts to develop robust cybersecurity strategies. It emphasizes the need for public awareness, international collaboration, and the integration of cybersecurity into the design phase of Smart City projects. The findings underscore the urgency for immediate investments, policy revisions, and collaborative efforts to strengthen the cybersecurity resilience of African Smart Cities. The paper concludes that addressing these challenges is essential for the successful and sustainable development of Smart Cities in Africa.